泡沫分离法与常规方法制备甘草酸粗品的比较.pdfVIP

泡沫贫离法与常规方法制备甘草酸粗品的比较 兰洁，杨明。，韩丽，苏艳桃，陈斯埔 (成都孛隧蕊大学药学院，匿j}|成都6t1130) 摘要：目11l勺与常规甘草酸粗品制备工艺比鞍，评价泡沫分离技术的特点。方法采用HPLC测定甘草酸的含量，比较泡沫 分离与水掇酸沉法、水掇醇沉法、稀氦水渗滤酸沉法、氨性己醇提酸沉法等4种常用工艺提取的时草酸转移率、甘草黻糨品纯 震、缝菠撬褰踺、工鼗等。绩暴滚滚分褰工艺掰分饔嚣嚣孳酸转移霉惫91，86％，爨瑟缝袭鸯32，34％，缝度提骞爨淹2，01。 结论泡沫分离技术藏耀于甘蕈魄蓊的分离有教而可行。 获键词：泡沫分离；甘嫩酸粗品；制铸工艺；转移率 孛垂分类鸶：R284．2，R927 文繁撩谈弱：矗 for betweenfoamfracfionafionandconventionalcrafts Comparison processing acidinclusion compound LAN Li，SU si—wei Jie，YANG Yah—tao，CHEN Ming。，HAN TradithmalChinese (School Universityof Medicine，Chengdu611130，China) of,Pharmacy，Chengdu Toevaluatethecharacteristicsoffoamfractionationin with Abstract：OBJECTIVE separatingglyeyrrhizicglycosid嬲bycomparing was 4conventionalcrafts．METHODSThecontentof acidwasdetermined fractionationcraft processing glycyrrhizic byHPLC，foam ammoniawater with4conventionalones(water—acidextraction，water—alcoholextraction，dilute percolation， compared processing ammonia—alcohol acidtransfer acidinclusion ratio extraction)interms ratio，purityofglyeyrrhiziccompound，elevation ofglycyrrhizie SO FoamfractionationhadSome acidtransferratioof of and on．RESULTS purity．1ift蝴一hour advantage，indudingglycyrrhizic of elevationratioof2．01。CONCLUSIONFoamffactionationiseffectiveandfeasible 91。86％，glycyrrhiziepurity32．34％，purity inseparatingglycyrrhizicglycosides。 acidinclusion ratio words：Foam