《A UPLC-DAD–MS Method for the Quality Analysis of ‘JiangYaBiFeng’Tablet》.pdf

《A UPLC-DAD–MS Method for the Quality Analysis of ‘JiangYaBiFeng’Tablet》.pdf

  1. 1、本文档共8页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
《A UPLC-DAD–MS Method for the Quality Analysis of ‘JiangYaBiFeng’Tablet》.pdf

Latin American Journal of Pharmacy Regular Article (formerly Acta Farmacéutica Bonaerense) Received: January 4, 2012 Revised version: February 1, 2012 Lat. Am. J. Pharm. 31 (1): 125-32 (2012) Accepted: February 5, 2012 A UPLC-DAD–MS Method for the Quality Analysis of ‘JiangYaBiFeng’ Tablet Lin ZHU, Siwei PENG, Olajide OLALEYE, Aidi QI, Xin CHAI, Haitao LIU Yuefei WANG * Tianjin State Key Laboratory of Modern Chinese Medicine and Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, 300193 Tianjin, PR China. SUMMARY. ‘JiangYaBiFeng’ (JYBF) tablet for treatment of hypertension in China is a composite pre- scription of Chinese and western medicines. By using ultra high performance liquid chromatography cou- pled with mass spectrometry (UPLC-MS), twenty-five compounds were simultaneously identified or tenta- tively characterized based on their retention times and MS spectra. Nine target compounds, hy- drochlorothiazide (HC), rutin, genistin, sophoricoside, baicalin, wogonoside, genistein, baicalein and wogonin, were further quantified by ultra high performance liquid chromatography with diode-array de- tector (UPLC-DAD). Chromatographic separation was successfully performed on a C18 column with gra- dient elution of 0.1 % formic acid aqueous solution and acetonitrile at the flow rate of 0.4 mL/min in 15 min at 52 °C. Different wavelengths were used to determine corresponding compounds to ensure the best resolution. According to the methodological validati

文档评论(0)

wfkm + 关注
实名认证
内容提供者

该用户很懒,什么也没介绍

1亿VIP精品文档

相关文档