原创力文档- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
查看更多
Abstract
ThisthesisfocusedontheSchmidtreactionof twocentral
azides，and contentswereincluded：f1)
alkyl
Schmidtreaction
ofaromatic withanazido ofSchmidtreactionof
aldehydes amine，and(2)design acyl
chlorideswith azidesandits inthe ontotal ofantofme．Inthefirst
alkyl applicationattempt synthesis part，
theexclusive wasobservedintheSchmidt
1．2-aryl reactionofaromatic with3．
migration aldehydes
theformalmetal—free ofaromaticwasachieved
azido-N-tosylpropan-1·amine，thenN-arylation aldehydes
Inthesecond substrateoftheintramolecularSchmidt
part，the reactionof chlorideswas
acyl designed．
and ofmethinewascontrolled．Thenthe ion
migration wasobtainedasintermediate
group n-acyliminium
andwas insituthearomatictobenzoindolizidine．Theconversion
capturedby ring was tothe
employed
onthetotal ofantofine．
attempt synthesis
In a fullreviewontheSchmidtreactionof andits in
chapter1，wepresented aldehydesapplication
ofnatural
synthesis products．
In andrealization Schmidtreaction is
chapter2，thedesign described．
ofaryl-migration ofarylaldehyde
Theexclusive ofan over was theformal
migrationaryl observed，with of
文档评论（0）