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SimulationInterestGroupScenarioTemplate-EMEDU.org.doc
Neuroleptic Malignant Syndrome Simulation Case
Title: Neuroleptic Malignant Syndrome
II. Target Audience: EM residents
Learning Objectives or Assessment Objectives
Primary
Develop and demonstrate an approach to the adult patient with hyperthermia and altered mental status
Demonstrate an understanding of the diagnosis and treatment of neuroleptic malignant syndrome
Secondary
Demonstrate an understanding of appropriate cooling methods for hyperthermia
Demonstrate the appropriate treatment of rhabdomyolysis
Develop a differential diagnosis for hyperthermia with AMS
Utilize closed loop communication
Critical actions checklist (attached)
Obtain a temperature reading in the altered mental status patient
Institute external cooling measures for severe hyperthermia
Obtain the medication history from the patient’s family member
Recognize the potential for neuroleptic malignant syndrome
Administer benzodiazepines for agitation
Do not administer succinylcholine for paralysis
Administer bromocriptine (or amantadine) dantrolene for NMS
Evaluate the patient for other causes of hyperthermia and AMS (infection, thyrotoxicosis, OD, substance intoxication / withdrawl)
Treat hypovolemia with crystalloid resuscitation
Treat rhabdomyolysis and ARF with crystalloid resuscitation (+/- urine alkalinization and mannitol)
Admit patient to the ICU
Environment
Lab Set Up – ED critical care room
Manikin Set Up – type of simulator, moulage, lines needed, drugs needed
High Fidelity Simulator
Moulage: Wig and street clothes for 24 y/o F
Lines: 2 peripheral IVs
IVFs: NS
Drugs Needed: code blue cart assumed
Dantrolene
Bromocriptine, amantadine
Versed, Ativan
Haldol, Droperidol
Cyproheptadine, Chlorpromazine
Paralytics: succinylcholine, vecuronium, atracurium
Sedatives: etomidate, ketamine
Props
EKG: Sinus Tachycardia
CXR: Normal
US: Cardiac US – hyperdynamic
IVC US – collapsible
Labs: CBC, BMP, LFTs, Coags, CK, Upt, UA, UTox, TSH, VBG, Lactate, Mag, Phos, APAP, ASA
12.8
CBC 19.7 490
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