a novel locus in the oxidative stress-related gene alox12 moderates the association between ptsd and thickness of the prefrontal cortex：在氧化应激相关基因的新位点的温和派alox12 ptsd和前额叶皮质的厚度之间的关系.pdfVIP

Psychoneuroendocrinology 62 (2015) 359–365 Contents lists available at ScienceDirect Psychoneuroendocrinology j o u rn al h omepage: w w w. elsev /locate/psy neuen A novel locus in the oxidative stress-related gene ALOX12 moderates the association between PTSD and thickness of the prefrontal cortex Mark W. Miller a,b,∗ , Erika J. Wolf a,b , Naomi Sadeh a,b , Mark Logue c,d,e , Jeffrey M. Spielberg b,f , Jasmeet P. Hayes a,b , Emily Sperbeck b , Steven A. Schichman g , Angie Stone g , Weleetka C. Carter g , Donald E. Humphries h , William Milberg i,j , Regina McGlinchey i,j a National Centerfor PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA b Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA c Research Service, VA Boston Healthcare System, Boston, MA, USA d Biomedical Genetics, Boston University School of Medicine, Boston, MA, USA e Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA f Neuroimaging Research for Veterans Center, VA Boston Healthcare System, Boston, MA, USA g Pharmacogenomics Analysis Laboratory, Research Service, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA h Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA, USA i Geriatric Research Educational and Clinical Center and Translational Research Centerfor TBI and Stress Disorders, VA Boston Healthcare System, Boston, MA, USA j Department of Psychiatry, Harvard Medical School, Boston, MA, USA a r t i c l e i n f o a b s t r a c t Article history: Oxidative stress has been implicated in many c