a novel low-energy electrotherapy that terminates ventricular tachycardia with lower energy than a biphasic shock when antitachycardia pacing fails：一种新的低能量电终止室性心动过速和较低的能量比双相冲击时，抗心动过速起搏失败.pdfVIP

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a novel low-energy electrotherapy that terminates ventricular tachycardia with lower energy than a biphasic shock when antitachycardia pacing fails：一种新的低能量电终止室性心动过速和较低的能量比双相冲击时，抗心动过速起搏失败.pdf

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a novel low-energy electrotherapy that terminates ventricular tachycardia with lower energy than a biphasic shock when antitachycardia pacing fails：一种新的低能量电终止室性心动过速和较低的能量比双相冲击时，抗心动过速起搏失败

Journal of the American College of Cardiology Vol. 60, No. 23, 2012 © 2012 by the American College of Cardiology Foundation ISSN 0735-1097/$36.00 Published by Elsevier Inc. /10.1016/j.jacc.2012.08.1001 Heart Rhythm Disorders A Novel Low-Energy Electrotherapy That Terminates Ventricular Tachycardia With Lower Energy Than a Biphasic Shock When Antitachycardia Pacing Fails Ajit H. Janardhan, MD, PHD,* Wenwen Li, PHD,† Vadim V. Fedorov, PHD,† Michael Yeung, MD,* Michael J. Wallendorf, PHD,‡ Richard B. Schuessler, PHD,†§ Igor R. Eﬁmov, PHD*† St. Louis, Missouri Objectives The authors sought to develop a low-energy electrotherapy that terminates ventricular tachycardia (VT) when antitachycardia pacing (ATP) fails. Background High-energy implantable cardioverter-deﬁbrillator (ICD) shocks are associated with device failure, signiﬁcant mor- bidity, and increased mortality. A low-energy alternative to ICD shocks is desirable. Methods Myocardial infarction was created in 25 dogs. Sustained, monomorphic VT was induced by programmed stimula- tion. Deﬁbrillation electrodes were placed in the right ventricular apex, and coronary sinus and left ventricular epicardium. If ATP failed to terminate sustained VT, the deﬁbrillation thresholds (DFTs) of standard versus exper- imental electrother