a randomized, blinded trial of uncooked cornstarch to diminish nocturnal hypoglycemia at diabetes camp:随机盲法试验,未煮过的玉米淀粉减少夜间低血糖在糖尿病夏令营.pdfVIP
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a randomized, blinded trial of uncooked cornstarch to diminish nocturnal hypoglycemia at diabetes camp:随机盲法试验,未煮过的玉米淀粉减少夜间低血糖在糖尿病夏令营
Diabetes Research and Clinical Practice 30 (1995) 2055209
A randomized, blinded trial of uncooked cornstarch to diminish
nocturnal hypoglycemia at Diabetes Camp’
Francine Ratner Kaufmana,*, Mary Halvorsona, Neal D. Kaufmanb
aDepartment of Pediatrics, Childrens Hospital Los Angeles and the University of Southern California School of Medicine,
Los Angeles, CA USA
bCedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA USA
Received 22 August 1995; revised 15 December 1995;accepted 19 December 1995
Abstract
Objective: To determine if uncooked cornstarch, as part of the evening snack, can avert nocturnal hypoglycemia in
type 1 diabetes. Research Design and Methods: Fifty-one campers and counselors at the American Diabetes
Association Camp in San Bernardino, CA were randomly assigned to receive 5 g of uncooked cornstarch as part of
the 21:00 evening snack vs. a standard snack of equivalent carbohydrate content. Each snack was given for five nights
and the participants and medical personnel were blinded as to assignment. Midnight and 07:OO finger stick blood
glucose levels were compared with values 60 mg/dl defined as hypoglycemia and values 250 mg/dl defined as
hyperglycemia. Results: There were 218 midnight and 222 07:OO values for comparison. There were six episodes of
hypoglycemia at midnight and nine episode
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