原创力文档a randomized, open-label, prospective, multicenter phase-iii clinical trial of elores in lower respiratory tract and urinary tract infections：一项随机，开放标签，前瞻性，对elores下呼吸道和尿路感染的多中心iii期临床试验.pdfVIP
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a randomized, open-label, prospective, multicenter phase-iii clinical trial of elores in lower respiratory tract and urinary tract infections：一项随机，开放标签，前瞻性，对elores下呼吸道和尿路感染的多中心iii期临床试验
j o u r n a l o f p h a r m a c y r e s e a r c h 6 ( 2 0 1 3 ) 4 0 9 e4 1 4
Available online at
journal homepage: www.el /locate/jopr
Original Article
A randomized, open-label, prospective, multicenter phase-III
clinical trial of Elores in lower respiratory tract and urinary
tract infections
Manu Chaudhary, Anurag Payasi*
Department of Cell Culture and Molecular Biology, Venus Medicine Research Centre, Baddi, Bhatoli Kalan, H.P 173205, India
a r t i c l e i n f o a b s t r a c t
Article history: Background: Lower respiratory tract infections (LTRIs) and urinary tract infections (UTIs) are
Received 20 March 2013 the leading causes of death world-wide. Treatment of these infections require the use of
Accepted 10 April 2013 antibiotics with enhanced activity against a broad spectrum of respiratory and urinary
Available online 3 May 2013 pathogens. This study was designed to study clinical and bacteriological efficacy as well as
tolerability of ceftiaxone þ disodium edtate þ sulbactam (the novel Antibiotic Adjuvant
Keywords: Entity; Elores) in adult patients in the treatment of lower respiratory tract infections (LRTIs)
Antibiotic adjuvant entity and urinary tract infections (UTIs).
Clinical trial Methods: A randomized, open-label, multicenter study was conducted on 297 patients
Elores which included 204 in UTIs and 93 in LRTIs. A total of 148 patients were there in Elores
Phase-III group with 102 cases of UTIs and 46 LRTIs; 149
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