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三七皂甙联合阿匹林治疗脑梗塞的临床观察
Clinical Observation Of Panax Notoginseng Saponins jointing
′
Aspirin s Treatment Of Cerebral infarction
Speciality:Hormonology of TCM
Author:Piao Meishun
Tutor:Prof.Yan Xiaoyan
Abstract
Objictive:This study selected notoginseng saponins (PNS )joint Aspirin and use of
Aspirin alone or notoginseng saponins for the treatment of Cerebral infarction, observed
the on hemorheology and carotid intimamedia thickness of the influence of learning, so as
to discusse PNS joint Aspirin application clinical effectiveness and safety.
Metehods: The 84 cases 0f clinically diagnosed as elderly patients with Cerebral
infarction was divided into three groups randomly, including Aspirin group, 29 cases,
100mg/d PO.;PNS group of 27 cases, 200mg general oral panax notoginseng, tid ,PO.and
Sanqi ( panax notoginseng) saponins joint Aspirin 28 cases,the jointed use of Aspirin
100mg/d PO,and panax notoginseng 200mg, tid PO. Three groups were observed for six
months. Three groups were observed Nerve function improvement,sickness′S change,
detection prothrombin time (PT), prothrombin time international standardization ratio (PT -
INR), D - dimers (D - D), platelet aggregation function (PAgT), allergic creactive protein
(CRP) and Carotid intima-media thickness. And to do bolld rution ,urine routine,feces
routine , feces occult blood as well as liver and kidney function tests,statistical analysis to
determine the efficacy and safety.
Results: Clinical observation found that three groups all can improve patients with
symptomatic, significantly extend PT, reduce PT - INR, D - D, PAgT and hs – CRP. Three
groups of comparison, notoginseng saponins prolonged PT effect is
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