从标本论治心肌死后心绞痛阳气虚衰证的临床研究.pdfVIP

The Clinical Research of Yang-Qi Deficiency Syndrome of Postinfaction Angina Pectoris from Biao and Ben Aspect Speciality: Clinical study on the treatment of heart system diseases with Traditional Chinese Medicine Tutor: Prof. Bao Peirong Author: Li Yahui Abstract Objective: To evaluate the effects of Pei Tu Yi Yuan Tang on Yang-Qi deficiency syndrome of postinfarction angina pectoris and investigate the mechanism of it. Methods: Divided 60 myocardial infarction patients into two groups equally. A group named treatment group, B group named control group. We gave Pei Tu Yi Yuan Tang to A group besides western medicine for one month. For B group, we only used the same western medicine. When the treatment cycle was over, we observed the effects of Chinese materia medica. Indexes including frequency of angina pectoris attacks, dynamic electrocardiogram, blood-fat, the function of blood vessel endothelium, P-selectin, Doppler echocardiography and Nt-pro BNP of blood serum were measured respectively. Results: Pei Tu Yi Yuan Tang obviously decreased the anginal frequency and the expression of TC、 TG、LDL-C 、LP(a) 、ET-1 、TXB2 、P-selectin 、Nt-pro BNP. It also increased the level of NO. In addition, this formula can improved the condition of Doppler echocardiography. Conclusion: Pei Tu Yi Yuan Tang has good effect to the patients of heart-stroke. Through this research, we think the mechanism including such aspects: improving the metabolic disorder of blood-fat, protecting the blood vessel endothelium, stabing the plaque, anti the activation of platelet, promoting thromboclasis, etc. In a word, this formula can protect the ventricular function and prevent myocardial infarction. Key words: Pei Tu Yi