儿童幽门螺杆菌染流行病学调查.pdfVIP

Investigation on Epidemiology of the H.pylori in Children Speciality: Internal Medicine of TCM Author: Li Yan Tutor: Prof. Li Yanning Abstract Objective：To investigate the infection status of H.pylori in children and related factors of children H.pylori infection, and to explore the relationship between the children H.pylori infection and the TCM syndromes of the disease correlated to H.pylori. Methods: To analyze the related factors of the children H.pylori infection , 400 children aged 3～14 years in Jinan were surveyed by epidemiological questionnaire(EQ). We distributed 400 questionnaires and retrieved 394 questionnaires, response rate was 98.5%. To evaluate the H.pylori infection status of the 394 children, the H.pylori stool antigen test were applied. Immediately 170 children who were finally diagnosed with H.pylori infection were surveyed by symptom questionnaire (SQ), and classified with syndrome differentiation in the children who had the disease correlated to H.pylori. We classified the body constitution by TCM Classification Standard and collected the tongue demonstration in the 170 children. We analyzed the relationship between the H.pylori infection and TCM syndrome type, tongue demonstration and body constitution. Result:The positive rate of the H.pylori stool antigen test in Jinan children was 43.2%; The total incidence of disease correlated to H.pylori was 60.6% in the H.pylori infection. The incidence of gastric abscess was 47.1%, the incidence of anorexia was 8.2%, and the incidence of urticaria was 5.3%. By single factor analysis in Our investigation, we screened 11 factors related H.pylori infection. By non-conditional and multivariate Logistic regression analysis, we find 4 major factors related H.pylori infection: age, shared b