原发性肝癌42例综合治疗分析.pdfVIP

原发性肝癌 420 例综合治疗分析 硕士研究生：沈波 导 师：王成友 教授 中文摘要 【目的】：总结本院原发性肝癌综合治疗方法和效果，讨论影响预后的因素,进一 步提高整体治疗效果。 【方法】:回顾性分析研究本院 420 例原发性肝癌病人的基本资料，治疗过程和 随访的资料，对比各个治疗组生存率；对104例根治性手术后早期复发的因素行 非条件Logistic 回归分析。 【结果和讨论】:手术组和非手术组1、3、5年的生存率分别是75.97%、41.69%、 26.50%；34.30%、7.29%、1.46%。综合治疗能提高手术切除率，降低术后复发率， 延长术后生存时间。对于不能手术治疗的肝癌，综合治疗能改善生活质量，延长 生存时间。本组实验表明手术组1、3、5年生存时间明显高于非手术组。肿瘤直 径＞5cm、肿瘤数目，AFP≥100ng/L是肿瘤复发独立的高危因素。 【结论】：肝癌治疗仍以手术为主，综合治疗为辅，综合治疗有助于提高生存率， 降低术后复发率，综合治疗有利于提高肝癌的治疗效果。 【关键词】原发性肝癌 综合治疗 生存分析 3 ABSTRACT 【objective 】:Summarize our comprehensive treatment of primary liver cancer, discuss the method and effect factors affecting the prognosis of overall, further improve the efficacy of treatment. 【Methods】:We retrospectively studied 420 cases of primary liver cancer patients basic material, treatment process and follow-up of material, contrast each treatment group survival rate；104 cases radical surgery to a recurrence of early after do unconditional Logistic regression analysis factors. 【Results and discussion】: the surgicalgroup and Non-surgical group 1, 3, 5 years survival rates respectively are 75.97%, 41.69%,26.50%; 0.3430%, 7.29% and 1.46%.Comprehensive treatment can improve the removal rate, reduce postoperative recurrence rate, extended postoperative survival time. For not the surgical treatment of liver cancer, comprehensive treatment can improve the quality of life, prolonging the survival time. Experiments showed that this occurred 1, 3, 5 year survival time was significantly higher than the scores. Tumor diameter 5cm, tumor numbe， AFP 100ng/L are independent risk factors of cancer recurrence . 【Conclusion 】:Liver cancer treatment can still primarily surgical, comprehensive treatment is complement