阿卡波糖干预治疗糖耐量异常的临床效果.docVIP

阿卡波糖干预治疗糖耐量异常的临床效果 　　[摘要] 目的 探讨阿卡波糖干预治疗糖耐量异常的临床效果。 方法 选择我院2012年2月～2013年2月收治的糖耐量异常患者，共86例。采用随机双盲法将其分成两组，对照组43例给予安慰剂治疗，研究组43例给予阿卡波糖干预治疗，比较两组患者的临床疗效及安全性。 结果 研究组患者23例显效，16例有效，4例无效；对照组19例显效，12例有效，12例无效，研究组治疗总有效率明显高于对照组（P中国论文网 /6/view-7216022.htm 　　[关键词] 阿卡波糖；干预治疗；糖耐量异常；双盲研究 　　[中图分类号] R977.1+5 [文献标识码] A [文章编号] 1674-4721（2016）02（a）-0120-03 　　Clinical effects of acarbose in the intervention and treatment of abnormal glucose tolerance 　　GAO Hong-yan 　　Outpatient Pharmacy，Maternal and Child Health Care Hospital of Yuanhui District in Luohe City of Henan Province，Luohe 462000，China 　　[Abstract] Objective To explore the clinical effects of acarbose in the intervention and treatment of abnormal glucose tolerance. Methods 86 patients with abnormal glucose tolerance who admitted to our hospital from February 2012 to February 2013 were selected.The double-blinded randomized method was applied and the patients were divided into two groups.43 patients in the control group were given placebo for the treatment，and 43 patients in the research group were given the intervention and treatment of acarbose.Clinical effects and safety between the two groups of patients were compared and analyzed. Results 23 patients in the research group were significantly effective，16 patients were effective，and 4 patients were ineffective；19 patients in the control group were significantly effective，12 patients were effective，and 12 patients were ineffective.The total effective rate of treatment in the research group was significantly higher than that in the control group（P 　　1 资料与方法 　　1.1 一般资料 　　选取我院2012年2月～2013年2月收治的糖耐量异常患者86例。诊断标准：7.8 mmol/L0.05），具有可比性。 　　1.2 方法 　　研究组患者在饮食控制、运动锻炼的基础上予以阿卡波糖，50 mg/次，3次/d；对照组患者在饮食控制、运动锻炼的基础上服用安慰剂，1片/次，2次/d，疗程均维持2个月。血标本测定：禁食1 d后次日早上8时空腹采集肘静脉血，分别测定患者的三酰甘油（TG）、血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）及胰岛素敏感指数（ISI）水平。 　　1.3疗效指标[6-7] 　　显效：治疗后，患者临床症状基本消失，2 h PBG36%，空腹血糖（FBG）15%，FBG 　　[3] 吴小飞，韩毛毛.3例运用康复训练仪的老年患者在预防老年长期卧床者糖耐量减退中的应用观察[J].按摩与康复医学（下旬刊），2012，3（10）：45-46. 　　[4] 刘欣，饶颖.201