从氨基酸到蛋白质研讨.ppt

For example, when some enzymes catalyze reactions, their active site changes structure. This catalysis mechanism is called an induced-fit. In some cases catalysis occurs without a change in structure at the active site; this is called a lock-and-key mechanism. Another example is ATP-synthetase. It has a collection of subunits that spin when the protein is exposed to a gradient of protons. One more example is allosteric regulation. In allosteric regulation, the activity of some proteins can be regulated by the binding of a small molecule to a regulatory site on the protein. An example of allo