移植肾CD20阳性淋巴细胞浸润的临床意义与受者中医分型特点.pdfVIP

13．33％ ，而脾肾阳虚型 6．67％ 和阴阳两虚型 2．22％ 相对较少。 中医证型 关键词：CD20阳性细胞移植肾预后 Clinical oftheInfiltrationofCD20-·Positive Significance inRenal andthe LymphocytesAllograftPathology DistributionofTCM ofthePatiens Syndrome Wu ehenguang Abs仃act 1 To theinfiltrationof inthe [Objective]analyze CD20-positivelymphocytes reactionofrenal theresults survival． 2 To reject allograft，correlatewith铲m thedistributionofTraditionalChinese ofthe explore withtheinfiltrationof patiens CD20-positivelymphocytes． Weexamined93 followdata from129 [Methods] integratedup biopsysamples renal in of General allografipatiems DepartmentUrology，FuzhouHospital， biopsied to maleis AreaCommandfrom 2003December2008．The NanjingMilitary February 67and is was cases female26．CD20 byimmtmochemistrystaining．These assayed weredividedintothree tothe ofCD20 cell groupsaccordingdegree positive infiltrationwith method：severe semiquantitative the infiltration _ 10％， 50％area andnegativegroup 10％area ．Toanalyze inthe ofrenal infiltrationof reaction lymphocytesrejeet allograft, CD20-positive correlatethe survival．toobservetheinfiltrationof results、 l，im伊aR CD20-positive TraditionalChinese whotreatmented lymphocytespatients by was and theroleinrenal followed postbiopsy explore allografl．Patient黟撒status for orfailure thecutoffdateofDecember3 documented 1， gr啦survival using 2005．Allcasesweretocollectinformationoftreatment，serum creatinine SCr ， and survival． albuminuria graft [Results]Three groups，severegroup I 50％arean 20 ，moderateinfiltration 10 ％， 50％area O％area all93 group l n 48 inpatients． n 25 andnegative of havenodifference、 l，inl timeandtimes 1 Threegroups age，gender,biopsy thetwelfthmonthofthe average transplantation P 0．05 ． 2 Infolio丽n争．1lp，the -3- SCrofsevere thanthatofmoderate higher group group 466．50士330．531xmol／L was moderateWas thanthatof 360．16士290．301maol／L P 0．05；thegroup higher survivalratioof group 276．79士240．78I，tmol／L P O．05． 3 Thegraft negative severe Waslowerthanthatofmoderateand 4