API3000LCMSMS操作培训手册调研报告.ppt

API 3000 Operator Training Course Analyst-NTFoster City CA PAL Lab;What is LC/MS;Element Mass;Natural isotopes Abundance;Natural Isotopes Abundance;Defining the masses;Examples of Masses;Multiply Charged Ions;Common adducts; GAS PHASE Acid-Base Scale for Positive Ion Neutral Molecules;GAS PHASE Acid-Base Scale for Negative Ions Neutral Molecules;Ionization Suppression;Basic steps of LC/MS analysis;API Analytical Domains;Quadrupole Theory;Quadrupole Theory (cont.);Resolution = 0.7 amu FWHH;Resolution = 0.6 amu FWHH;Resolution = 0.5 amu FWHH;Quadrupole Theory Ion Energy;Quadrupole Theory Ion Energy;Ion Energies;Ion Energies;Resolution definition for Magnetic Sector instruments; API3000 Hardware Overview;API3000 PERFORMANCE:;API- 3000 Ion Path ;System Overview;API3000 Gas Function and Setting;10 port valco valve configuration;10 port valco valve configuration;10 port valco valve configuration;Sample Introduction Methods;Ionization Sources;Ionization Sources:TurboIonSpray;TurboIonSpray Source:;TurboIonSpray - Ion Evaporation;TurboIonSpray (cont.);TurboIonSpray (cont);TurboIonSpray (cont);TurboIonSpray (cont);TurboIonSpray (cont);Heated Nebulizer (cont.);Heated Nebulizer (cont.);Heated Nebulizer Inlet;Atmospheric Pressure Chemical Ionization (APCI);Atmospheric Pressure Chemical Ionization (APCI);Heated Nebulizer - APCI;Heated Nebulizer - APCI;Vacuum Interface: Curtain GasDifferentially Pumped Interfaces;Vacuum Interface: Curtain Gas Differentially Pumped Interfaces;Vacuum System;Vacuum Interface: Curtain Gas Differentially Pumped Interfaces;Analyzer - Q0 Region;API-3000 Ion Path;Analyzer - IQ1, ST RO1;API- 3000 Ion Path (cont);API-3000 Mass Filter Rail;API-3000 Collision Cell - Linac;Collisional Focusing;PE-Sciex’s LINAC Technology;Generation of the LINAC Axial Field Gradient;Ion Path Linac “Off”;Ion Path with Linac ;Selegiline response with different MRM dwell times;Effect of dwell time on resolution precursor ion scan mode; Q1 full scan Q3 full sc