痰热清注射液对COPD急性加重期患者IL6及IL10影响.pdfVIP

Tanreqing injection for COPD patients with Acute aggravating period of IL一6 and IL一10 ABSTRACT Objective：蹦s study through the observation of Tanreqing injection on chromc obstructive pulmonary disease(chromc obstructive pulmonary diseases．COPD)in patients with acute aggravating period of clinical symptoms，signs，and before and after treatment sertlm interleukin 6(IL 6) and interleuldn 1 0(IL一1 0)，changes in the levels of c—reactive protein(CPR)， from the Angle of the inhibition of lung airway inflammation clear Tanreqing injection in the treatment of COPD exacerbations mechanism，and further guide the clinical use of the plllegrn hot clear． Methods：By random method，collecting of 60 cases of our hospital respiratory medicine in patients，all patients were diagnosed with COPD acute phase(September 20 1 3一February 20 1 4)，according to the random Numbers are divided into the control group(routine treatment)and treatment group (conventional treatment+Tanreqing inj ection)，all the 23 cases in each group， two groups of patients were given anti—infection，stop coughing，low flow oxygen，such as conventional treatment，the treatment group on the basis of conventional treatment combmed with Tanreqing inj ection 20 ml／d，a total of 7 days，all the patients 1 days prior to the treatment and after treatment respectively(day 8)symptom score and the detection of serum IL一6，IL I O and CI冲content changes． Results：Tanreqing inj ection can reduce the COPD patients witll acute phase serum IL一6，CPR content，increase the content of IL一10俨O．05) 一 ‘．● o r一 ’ ’ ’ ’ ’ -’ 』 compared wi扯l controls．1anreqmg mjectlon Can improve tlae acute aggravating period of COPD patients’symptoms，signs，signs integral． compared、vith control group俨O．05)． Conclusion(s)：Tanreqing inj ection Call decrease the serum IL一6，CPR content，improve the content of IL一1 0，and can improve clinical symptoms and signs in patients with acute aggravating period of COPD，prove that Tanreqing inj ection can inhibit cell inflammatory cytokine