大柴胡汤对肝郁气滞型急性胰腺炎患者血清IL1β和IL6影响.pdfVIP

有统计学意义(P(O．01)。 研究结论： 经中医辨证论治后，对中医证型(即肝郁气滞型)对应的患者，使用中药(大 柴胡汤)内服配合西医常规治疗轻症急性胰腺炎对血清中IL—l B和IL一6浓度下调 作用明显，说明大柴胡汤可以通过下调肝郁气滞型急性胰腺炎患者外周血血清中 IL．1 13、IL．6的浓度来改善急性炎症反应程度。证明用大柴胡汤配合西医常规方 法治疗轻症急性胰腺炎能更有效清除循环中产生的炎性因子，有利于减轻组织损 伤，阻止病情的发展，有利于机体免疫功能的恢复，对轻症肝郁气滞型急性胰腺 炎的治疗有一定的作用。 关键词：大柴胡汤；轻症急性胰腺炎；肝郁气滞型；白介素-1 13；白介素一6 II The treatment of acute pancreat i t i S of I i vet O i stagnat；on affected by Dacha i hutang on serum l L一1．I L-6 Speciality：oral taking of TCM combined with Western Medicine Auther：Cheng Jing Tutor：Cheng Yu——xing Professor Abst ract Background Mild acute pancreatitis is one of comillon acute abdomen surgery disease， and the incidence rate of it iS from 80％。85％of occupied the whole acute pancreatitis．For thiS disease，medical treatment for simple monotonic， expensive treatment cost，longer treatment time．The disease in the treatment by surgical operation treatment to non operation treatment and conservative． In the current clinical treatment，it has become an important method for treatment of thiS di sease wi th integrated traditional Chinese and Western medicine，but it iS not clear of the mechanism of traditional Chinese medicine in the treatment of acute pancreatitis．ThiS topic through the use of conventional treatment of Western medicine combined with oral Dachaihu decoction，dynamic observation of Dachaihu Decoction on acute pancreatitis(i．e．，acute pancreatitis of liver qi stagnation type)in patients with serum interleukin一1 beta(IL一1 B)， interleukin-6(IL-6) effect of concentration index changes，study the possible mechanism of Dachaihu Decoction in the treatment of mild acute pancreatitis patients of liver qi stagnation type． Objective According to the efficacy of traditional Chinese medicine and pharmacology of features of Dachaihu decoction。observe the impact of IL—l B and IL一6 in serum of peripheral blood using Dachaihu Decoction plus medical therapy on the patients with mild acute pancreatitiS，evaluation of the clinical effect of Dachaihu Decoction Treatment of mild