磷脂酰丝氨酸.pptVIP

* 黄文龙 2016-03-05 Abstract: PS is also profoundly dysregulated in the tumor microenvironment and antagonizes the development of tumor immunity. In this review, we discuss the biology of PS with respect to its role as a global immunosuppressive signal and how PS is exploited to drive diverse pathological processes such as infection and cancer. Finally, we outline the rationale that agents targeting PS could have significant value in cancer and infectious disease therapeutics. 1.PS Asymmetry in Biological Membranes 2.Mechanisms of PS Externalization during cell Stress and Apoptosis Al