氨氯地平与缬沙坦治疗高血压病的临床效果比较.docVIP

氨氯地平与缬沙坦治疗高血压病的临床效果比较 　　[摘要] 目的 比较苯磺酸氨氯地平片与缬沙坦胶囊治疗高血压病的临床效果。 方法 选取2009年10月～2012年10月在本院就诊治疗的120例高血压病患者作为研究对象，按照治疗方法的不同分为治疗组（62例）和对照组（58例）。治疗组给予苯磺酸氨氯地平片，对照组给予缬沙坦胶囊，比较两组治疗前后的舒张压和收缩压水平，评价其疗效与不良反应。 结果 治疗组的总有效率为82.3%，显著高于对照组的74.1%，差异有统计学意义（P0.05）。两组治疗后的舒张压和收缩压显著低于治疗前，差异有统计学意义（P0.05）。治疗组治疗后的舒张压和收缩压显著低于对照组治疗后，差异有统计学意义（P0.05）。治疗组的不良反应主要有头痛1例和水肿3例，对照组的不良反应主要有干咳5例、头晕和疲乏各1例。 结论 苯磺酸氨氯地平片治疗高血压病效果优于缬沙坦胶囊。 　　[关键词] 高血压病；氨氯地平；缬沙坦 　　[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721（2016）02（b）-0131-03 　　Clinical effect comparison of amlodipine and valsartan in the treatment of hypertension disease 　　ZHONG Fei-peng 　　Department of Emergency，Enping Branch of Wuyi Hospital of Traditional Chinese Medicine of Enping City in Guangdong Province，Enping 529400，China 　　[Abstract] Objective To compare the clinical effect of amlodipine besylate tablet and valsartan capsule in the treatment of hypertension disease. Methods 120 cases of hypertension from October 2009 to October 2012 in our hospital were selected and divided into the treatment group （n=62） and the control group （n=58） according to different treatment methods.The treatment group was given amlodipine besylate tablet，the control group was given valsartan capsule.The level of diastolic blood pressure and systolic blood pressure before and after treatment was compared in the two groups，and the effect and adverse reaction was evaluated. Results The total effective rate in the treatment group was 82.3%，which was higher than 74.1% in the control group，with significant difference （P0.05）.The diastolic blood pressure and the systolic blood pressure in the two groups after treatment was lower than that before treatment，with significant difference （P0.05）.The diastolic blood pressure and the systolic blood pressure in the treatment group after treatment was lower than that in the control group after treatment，with significant difference （P0.05）.The main adverse effects of the treatment group were headache （n=1） and edema （n=3），which were dry