液基细胞学检查与阴道镜对宫颈癌前病变的诊断价值分析.docVIP

液基细胞学检查与阴道镜对宫颈癌前病变的诊断价值分析 　　[摘要] 目的 探析液基细胞学检查（TCT）与阴道镜对宫颈癌前病变的诊断价值。方法 整群选择2013年1月―2015年2月收治的96例采取液基细胞学检查与阴道镜筛查宫颈癌前病变的患者，并与病理学检查结果进行对比分析。 结果 TCT对低级别病变（CIN I）及高级别病变（CIN II、CINIII、癌变）的诊断符合率为53.33%、80.0%；阴道镜对低级别病变及高级别病变的诊断符合率为63.64%、64.29%；阴道镜对低级别病变符合率63.64%%显著高于TCT（χ2=6.793，P0.05）；TCT对高级别病变诊断符合率80.0%显著高于阴道镜（χ2=7.902，P0.05）。 结论 TCT与阴道镜对宫颈癌前病变的诊断各有利弊，两者联合能够提高诊断符合率。 　　[Abstract] Objective To discuss the value of thinprep cytology test and colposcope in diagnosis of precancerous lesions of uterine cervix. Methods 96 cases of patients with precancerous lesions of uterine cervix tested by thinprep cytology and screened by colposcope from January 2013 to February 2015 were selected， and were given comparative analysis with pthological examination results. Results The accordance rate of TCT in diagnosis of low-grade lesions（CINI）and high-grade lesions（CINII， CINIII， canceration）was respectively 53.33% and 80.0%， the accordance rate of colposcope in diagnosis of low-grade lesions and high-grade lesions was respectively 63.64% and 64.29%， the accordance rate of colposcope in diagnosis of low-grade lesions was obviously higher than that of TCT（χ2=6.793，P0.05）； the accordance rate of TCT in diagnosis of high-grade lesions was 80.0%， which was obviously higher than that of colposcope（χ2=7.902，P0.05）. Conclusion TCT and colposcope in diagnosis of precancerous lesions of uterine cervix have their advantages and disadvantages， and the combination of the both can improve the diagnostic accordance rate. 　　[Key words] TCT； Colposcope； Precancerous lesions of uterine cervix 　　宫颈癌的发展和HPV感染有关，当机体内长期处于HPV感染的状态，便会诱发宫颈癌。目前，对于宫颈癌的预防均是通过早期筛查及干预进行实现的，液基细胞学、阴道镜检查是非常常见的一种筛查方法，检出率较好[1-2]，为探析TCT与阴道镜对宫颈癌前病变的诊断价值，该研究将2013年1月―2015年2月收治的96例采取液基细胞学检查与阴道镜筛查宫颈癌前病变的患者作为研究对象，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　整群选取2013年1月―2015年2月收治的96例采取液基细胞学检查与阴道镜筛查宫颈癌前病变的患者，年龄22～68岁，平均（46.9±6.3）年，绝经患者40例，非绝经患者56例，具有性生活史，无宫颈手术史及子宫切除史。给予常规检查后进行TCT检查，对于结果异常的患者进行阴道镜及病理活检。 　　1.2 方法 　　TCT检查：应用窥阴器将宫颈暴露，擦去表面分泌物，将细胞刷插入宫颈内口，旋转