深圳地区宫颈上皮内瘤变中高危型HPV感染型别和危险因素分析.docVIP

深圳地区宫颈上皮内瘤变中高危型HPV感染型别和危险因素分析 　　【摘要】 目的：总结深圳地区宫颈上皮内瘤变中高危型HPV（乳头瘤病毒）感染型别，探讨其危险因素。方法：选取2012年10月-2014年10月于本院接受宫颈癌筛查的患者500例作为研究对象，对其宫颈上皮内瘤变中的HPV感染类别进行统计、分析，确定其危险因素。结果：深圳地区最常见的感染类别为HPV16，其次为HPV58、52、33、18，此外，多因素分析结果显示，经济收入低、被动吸烟、人工流产、第一次性生活年龄小为HPV感染的独立危险因素（P0.05）。结论：HPV感染率随着宫颈细胞学病变级别的增高而增高，深圳地区不同宫颈上皮内瘤变患者中HPV感染类别相对单一，为降低宫颈癌发病率，深圳地区应针对HPV感染的危险因素加强健康宣教工作。 　　【关键词】 深圳地区； 宫颈上皮内瘤变； 高危型HPV感染； 型别； 危险因素 　　Analysis on Categories and Risk Factors of High-risk HPV Infection in Cervical Intraepithelial Neoplasia in Shenzhen Area/LI Xiao-yan，LUO Li-dan，WU Gui-qun，et al.//Medical Innovation of China，2016，13（04）：005-008 　　【Abstract】 Objective：To conclude the categories and risk factors of high-risk HPV（human papilloma virus） infection in cervical intraepithelial neoplasia in Shenzhen area.Method：500 patients who accepted cervical cancer screening in our hospital from October 2012 to October 2014 were selected as the research objects.The categories of high-risk HPV infection in cervical intraepithelial neoplasia were counted and the risk factors were determined.Result：In Shenzhen，the most common infection category was HPV16 and then were HPV58，52，33，18.What’s more，as the results of multivariate analysis showed，low income，passive smoking，abortion and the first sexual life at early age were the independent risk factors of HPV infection（P0.05）.Conclusion：The infection rate of HPV increases as the level of cervical cytology lesions increases.The HPV infection categories of patients with cervical intraepithelial neoplasia in Shenzhen area are rather simplex.In order to decrease the morbidity of cervical cancer，Shenzhen area shall enhance health education aiming at the risk factors of HPV infection. 　　【Key words】 Shenzhen area； Cervical intraepithelial neoplasia； High-risk HPV infection； Categories； Risk factor 　　First-author’s address：Pingshan New District People’s Hospital of Shenzhen City，Shenzhen 518118，China 　　doi：10.3969/j.issn.1674-4985.2016.04.002 　　宫颈癌严重危害着妇女的身心健康，HPV在宫颈癌的