茵栀黄口服液联合间隙蓝光照射佐以双歧杆菌三联活菌治疗新生儿黄疸的临床观察.docVIP

茵栀黄口服液联合间隙蓝光照射佐以双歧杆菌三联活菌治疗新生儿黄疸的临床观察 　　[摘要] 目的 探讨茵栀黄口服液联合间隙蓝光照射佐以双歧杆菌三联活菌治疗新生儿黄疸的临床效果。 方法 分析2012年3月～2015年3月内江市第一人民医院收治的120例新生儿黄疸患儿的临床资料，依据治疗措施不同进行分组，对照组40例给予常规治疗，联合治疗组80例给予茵栀黄口服液联合间隙蓝光照射佐以双歧杆菌三联活菌治疗。观察两组新生儿黄疸治疗前后经皮胆红素水平、治疗时间、临床疗效和不良反应发生率。 结果 治疗前对照组和联合治疗组患儿经皮胆红素水平[（312.3±50.4）、（309.8±48.4）μmol/L]与治疗后[（176.7±22.4）、（125.8±18.7）μmol/L]比较，差异均无统计学意义（P 0.05）；治疗后两组患儿经皮胆红素均低于治疗前，治疗后联合治疗组低于对照组，差异均有统计学意义（P 0.05）。联合治疗组患儿的日均胆红素下降值[（46.8±8.7）μmol/L]、治疗时间[（3.4±0.3）d]均优于对照组[（33.6±9.1）μmol/L、（5.0±1.0）d]，联合治疗组总有效率（100%）高于对照组（90%），总不良反应发生率（11.3%）低于对照组（45.0%），差异均有统计学意义（P 0.05）。 结论 茵栀黄口服液联合间隙蓝光照射佐以双歧杆菌三联活菌可明显改善新生儿黄疸患儿的临床症状，疗效良好，值得临床推广应用。 　　[关键词] 茵栀黄口服液；间隙蓝光照射；双歧杆菌三联活菌；新生儿黄疸 　　[中图分类号] R272.1 [文献标识码] A [文章编号] 1673-7210（2016）04（b）-0096-04 　　[Abstract] Objective To approach clinical curative effect of treatment neonatal jaundice by Yinzhihuang Oral Solution combined with clearance of blue light and bifidobacterium triple viable. Methods Clinical data of 120 cases with neonatal jaundice in the First Peoples Hospital of Neijiang City from March 2012 to March 2015 were analyzed， they were divided into two groups according to the treatment methods， 40 cases of control group were given conventional treatment， 80 cases of combination group were given Yinzhihuang Oral Solution combined with clearance of blue light and bifidobacterium triple viable treatment. The levels of percutaneous bilirubin， time of therapy， clinical effects and incidence of adverse reaction of two groups before and after treatment were observed. Results Levels of percutaneous bilirubin in the control group and combination group [（312.3±50.4）， （309.8±48.4） μmol/L] before and after treatment [（176.7±22.4）， （125.8±18.7） μmol/L] had no statistically significant differences （P 0.05）； levels of percutaneous bilirubin of two groups after treatment were lower than those before treatment， the percutaneous bilirubin of the combination group after treatment was lower than that of the control group， the differences were stati