荆芥炭方联合雷公藤多苷片治疗进行性色素性紫癜性皮肤病的临床效果.docVIP

荆芥炭方联合雷公藤多苷片治疗进行性色素性紫癜性皮肤病的临床效果 　　[摘要] 目的 探讨荆芥炭方联合雷公藤多苷片治疗进行性色素性紫癜性皮肤病的临床效果。 方法 选取2012年1月～2014年12月我院收治的100例进行性色素性紫癜性皮肤病患者作为研究对象，按照随机分配的原则，将患者分为对照组和观察组，每组50例。对照组给予肝素钠乳膏治疗，观察组给予荆芥炭方联合雷公藤多苷片治疗。每组患者均进行为期1个月的治疗。治疗1个月后，比较两组患者的治疗效果和不良反应发生情况。 结果 对照组的总有效率为64%，观察组为86%，观察组的治疗效果明显优于对照组（χ2=6.4533，P=0.011）。对照组中共有18例患者发生不良反应，不良反应发生率为36%，观察组中共有9例发生不良反应，不良反应发生率为18%，观察组患者的不良反应发生情况明显低于对照组（χ2=4.1096，P=0.043）。 结论 荆芥炭方联合雷公藤多苷片治疗进行性色素性紫癜性皮肤病，不仅具有显著的临床效果，还具有较高的安全性，具有较高的临床价值，可考虑被广泛应用于该病的治疗中。 　　[关键词] 荆芥炭方；雷公藤多苷片；进行性色素性紫癜性皮肤病；临床效果；不良反应 　　[中图分类号] R758.6 [文献标识码] A [文章编号] 1674-4721（2015）09（b）-0146-03 　　Clinical effect of Carbonized catnip prescription combined with Tripterygium glycosides tablet in treatment of progressive pigmentary purpuric dermatosis 　　YAO Hui-rong 　　Department of Dermatology，Jingdezhen Dermatology Hospital in Jiangxi Province，Jingdezhen 333000，China 　　[Abstract] Objective To explore the clinical effect of Carbonized catnip prescription combined with Tripterygium glycosides tablet in the treatment of progressive pigmentary purpuric dermatosis. Methods One hundred patients with progressive pigmentary purpuric dermatosis admitted into our hospital from January 2012 to December 2014 were selected as the study subjects and divided into control group and observation group according to the random allocation principle，and there were 50 patients in each group.Control group was given heparin sodium cream treatment and observation group was given Carbonized catnip prescription combined with Tripterygium glycosides tablet treatment.Both groups of patients were treated for 1 month.After 1 moth treatment，the clinical treatment effect and occurrence of adverse reaction between two group groups was compared respectively. Results The total effective rate of control group was 64% and that of observation group was 86%，the observation group was significantly better than the control group in the clinical effect （χ2=6.4533，P=0.011）.Adverse reactions occurred in 18 patients of control group