新药临床试验剖析.ppt

* * * * CRF 病例报告表 IRB Institutional Review Board 机构审评委员会 PI Principal investigator主要研究者 * * * Overhead 8 Trainer’s Script Show Read Overhead Out of thousands of compounds tested, only a handful make it past the laboratory stage. The first step in developing a drug is when scientists search for a chemical compound that has the effects they want. This is known as the Research or Discovery phase. Testing begins in chemistry labs and progresses to animals and finally to humans referred to as Clinical Trials , if the experimental drug shows promise. Toxic effects or other problems redu