第二章 细胞的基本功能31课件.pptVIP

* ５、AP propagation-the local Circuit (局部电流) The propagation of AP along unmyelinated nerve fibers is usually explained with the local Circuit．Flow or Local Current theory． Fig. 2－6 depicts the propagation of action potentials in an unmyelinated nerve fiber. 有髓纤维－－跳跃式传导Propagation AP along myelinated nerve fibers is usually explained with the “Saltatory Conduction” theory（Fig.2－7）．At the point of excitation，the membrane is depolarized，the outside becoming negative and the inside becoming positive. This causes electrical currents flow from the adjacent areas towards the depolarized area in a manner essentially similar to that occurred in unmyelinated nerve fibers. However, since the myelin sheath is a good insulator, the electrical current must reach the next node of Ranvier in order to flow across the membrane to complete the circuit. The entry of electrical current at the node causes depolarization of the nodal region which again induces electrical current flow. Thus, the electrical current flows through the surrounding extracellular fluid and the axoplasm from node to node, exciting successive nodes one after another. The jumping of depolarization from node to node is called “Saltatory Conduction”. * ５、AP propagation-the local Circuit (局部电流) The propagation of AP along unmyelinated nerve fibers is usually explained with the local Circuit．Flow or Local Current theory． Fig. 2－6 depicts the propagation of action potentials in an unmyelinated nerve flber. 有髓纤维－－跳跃式传导Propagation AP along myelinated nerve fibers is usually exolained with the “Saltatory Conduction” theory（Fig.2－7）．At the point of excitation，the membrane is depolarized，the outside becoming negative and the inside becoming positive. This causes electrical currents flow from the adjacent areas towards the depolarized area in a manner essentially similar to that occurred in unmyelinated nerve fibers. However, since the myelin sheath is a good insulator, the electrical current must reach the next node of R