痴呆与阿尔茨海默病_培训课件.pptVIP

This study, was designed with the intention of spefically focussing on neurospychitaric features in a rpct model..patients had to have npi scores 11 to enter and form at least3 domains so that a variety of sysmtoms could be examined. Withdrawal of donepezil after 12 weeks of open-label treatment showed a significant worsening of neuropsychiatric symptoms compared with those patients continuing donepezil treatment.Treatment effect size of around 6 points in the randomised arm NPI subitem score data show that donepezil treatment significantly improves behavioral symptoms across 9 behavioral subi