第讲急性肾损伤AKI_培训课件.pptxVIP

急性肾损伤Acute Kidney Injury (AKI)浙江大学邵逸夫医院肾脏科 叶有新浙江大学附属邵逸夫医院肾脏科 叶有新 肾 脏 解 剖Anatomy of the Kidney正常肾脏功能Renal function排除毒素 Excretion of toxin维持机体水、电解质和酸碱平衡 Maintaining water,electrolytes and acid-base balance内分泌 Endocrine急性肾衰定义（ARF)DEFINITION由各种病因引起的肾功能急骤进行性减退而出现的临床综合症，主要表现为毒素蓄积，水电解质酸碱平衡失调。AKI represents an abrupt decrease in the ability of the kidney to excrete nitrogenous wastes,resulting in azotemia, fluid retaintion, electrolyte disturbance and metabolic acidosis.急性肾损伤（AKI ）诊断标准血肌酐48小时内升高≥0.3mg/dl，增至基数值150%以上；或尿量＜0.5ml/kg/h大于6小时1期Scr ↑ ≥0.3mg/dl ≥150% U V ＜0.5ml/kg/h ＞6h2期 Scr ↑基数值＞200%