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Bipolar DisorderandSubstance Use Disorders Bipolar I Disorder Includes one or more Manic Episodes or Mixed Episodes, sometimes with Major Depressive Episodes as well Single Manic Episode Most Recent Episode Hypomanic Most Recent Episode Manic Most Recent Episode Mixed Most Recent Episode Depressed Manic Episode A period of unusual and ongoing elevated, expansive, or irritable mood, of at least 1 week duration Manic Episode Three (3) or more of the following occur: Inflated self-esteem or grandiosity; Decreased sleep needs; More talkative than usual; Racing thoughts; Distractibility; Increase in activity or psychomotor agitation; Excessive involvement in pleasurable activities with high potential for painful consequences (ex. spending, sex). Manic Episode The mood disturbance is severe enough: to significantly impair occupational functioning, or to significantly impair usual social activities or relationships, or to require hospitalization to prevent harm to self or others Manic Episode Symptoms are NOT due to the direct effects of a substance (including prescribed medication and/or intoxication or withdrawal syndromes of substances of abuse), or a general medical condition Hypomanic Episode A period of unusual and ongoing elevated, expansive, or irritable mood, lasting through at least 4 days, that is clearly different from the usual non-depressed mood Manic symptoms (see) Significant functional impairment Symptoms are NOT due to substances of abuse Cocaine Intoxication Euphoria (elevated, expansive mood) Changes in sociability (more talkative) Hypervigilance Interpersonal sensitivity (irritability) Anxiety, tension or anger Impaired judgment Impaired social or occupational functioning Psychomotor agitation Alcohol Withdrawal Insomnia Psychomotor agitation Anxiety Hand tremor Temporary hallucinations Nausea, vomiting Seizures Impaired social or occupational functioning Depressive Episode Five or more of the following are present during the same 2-week pe
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