辅助性T淋巴细胞的研究进展.pptVIP

Trends in Helper T cells Th1/Th2 Balance Th1 Cells Th1 cells?are produced when dendritic cells and pre-Th cells form an?immunological synapse?in which the dendritic cell presents antigen to the T cells receptor for antigen (TCR), and secretes interleukin 12 (IL-12) as well as interleukin 18 (IL-18) and IFN-γ (not shown). These stimulate macrophages to kill the bacteria they have engulfed; recruit other leukocytes to the site producing?inflammation; act on B cells to promote antibody?class switching. Th2 Cells Th2 cells are produced when?antigen-presenting cells?(APCs) present antigen (e.g.,?