腹腔镜与开腹胃癌根治术在进展期胃癌中的临床疗效及对细胞免疫功能的影响.docVIP

腹腔镜与开腹胃癌根治术在进展期胃癌中的临床疗效及对细胞免疫功能的影响 　　[摘要] 目的 比较腹腔镜根治术与传统开腹术在进展期胃癌中的临床疗效及对细胞免疫功能的影响。 方法 选择2010～2012年丽水市人民医院收治胃癌患者106例，随机分为观察组和对照组，每组各53例，观察组接受腹腔镜根治术，对照组接受传统开腹术治疗，比较两组患者的近期疗效及细胞免疫功能。 结果 ①观察组患者切口长度、手术时间、术中出血量、术后排气时间、术后住院时间分别为（7.28±1.23）cm、（168.12±28.36）min、（131.24±26.57）mL、（3.24±1.26）d和（11.39±2.84）d，与对照组比较，差异均有统计学意义（t = 11.477、6.163、7.456、5.685、4.534，P 0.05）。②术后观察组患者CD4+、CD4+/CD8+分别为（27.21±3.98）%和（0.89±0.16），与对照组比较，差异有统计学意义（t = 6.153、4.979，P 0.05）。 结论 腹腔镜根治术治疗胃癌的近期临床效果优于传统开腹术，并且对患者的细胞免疫功能抑制作用较轻，值得临床推荐。 　　[关键词] 胃癌；腹腔镜；传统开腹术；临床疗效；细胞免疫功能 　　[中图分类号] R735.2 [文献标识码] A [文章编号] 1673-7210（2014）01（c）-0064-04 　　Comparison on short-term clinical efficacy and cellular immune function of laparoscopy-assisted radical gastrectomy and traditional laparotmy in the treatment of gastric cancer 　　MOU Li1 QIAN Rong2 　　1.Department of General Surgery， the Peoples Hospital of Lishui City， Zhejiang Province， Lishui 323000， China； 2.Department of General Surgery，the Peoples Hospital of Zhejiang Province， Zhejiang Province， Hangzhou 310014， China 　　[Abstract] Objective To compare the short-term clinical efficacy and cellular immune function of laparoscopy-assisted radical gastrectomy and traditional laparotmy in the treatment of gastric cancer. Methods A total of 106 patients with gastric cancer in the Peoples Hospital of Lishui City from 2010 to 2012 were selected and divided into observation group and control group with 53 cases in each group. Patients in observation group were treated with laparoscopy-assisted radical gastrectomy and the control group was treated with traditional open surgery. The short-term clinical efficacy and cellular immune function were compared in the two groups. Results ①Length of cut， duration of operation， amount of blood loss during operation， evacuation time after operation， and hospital stays after operation in observation group were （7.28±1.23） cm， （168.12±28.36） min， （131.24±26.57） mL， （3.24±1.26） d and （11.39±2.84） d respectively， the differences we