56例膀胱肿瘤术前术后经药物膀胱灌注的临床效果观察.docVIP

56例膀胱肿瘤术前术后经药物膀胱灌注的临床效果观察 　　摘要：目的：探究并分析56例膀胱肿瘤患者术前术后经药物膀胱灌注的临床效果。方法：选取我院自2010年2月～2011年2月收治的膀胱肿瘤患者56例，将其作为研究对象，随机分为A、B两组，每组各28例。两组患者都进行保留膀胱的手术治疗。A组患者在手术后对其进行定期药物膀胱灌注，即为观察组；B组患者在进行肿瘤治疗手术后，不进行药物灌注，即为对照组。观察两组患者术后的身体状况和肿瘤复发率。结果：术后经过膀胱药物灌注的膀胱肿瘤患者肿瘤复发率明显低于未进行膀胱药物灌注的肿瘤患者，p0.05，具有统计学意义。结论：膀胱手术后进行药物膀胱灌注能有效的降低肿瘤复发率，达到阻碍肿瘤复发的目的，值得在临床上广泛推广。 　　关键词：膀胱；肿瘤；药物灌注；效果观察 　　The clinical effect observation of 56 cases of irrigating bladder by using drugs before and after bladder tumor surgery 　　Gao Weicheng 　　Abstract：Objectives：To study and analyse clinical effect of 56 cases irrigating bladder by using drugs before and after bladder tumor surgery.Methods：Chose 56 cases of those bladder tumor patients who have been admitted at our hospital from February 2010 to february 2011 as study objectives，and divided them into group A and group B，each group has 28 cases.Proceeded surgery which kept bladder as treatment to all of them.Regularly used drugs to irrigate group As patients bladder after the surgery，namely observation group；While did not use drugs to irrigate group Bs patients bladder after the surgery，namely control group.Observed these two groups patients physical condition after surgery and tumor recurrent rate.Results：Those bladder tumor patients who have been received drugs to irrigate their bladder after the surgery，their tumor recurrent rate was obviously lower than those who have not use drugs to irrigate their bladder.p0.05，and it has statistics meaning.Conclusions：Adopting drugs to irrigate bladder after the bladder operation can lower tumor recurrent rate，and reach the purpose of preventing tumors recurrence，and it is worthy of clinical promotion. 　　Key Words：bladder；tumor；perfusion；effect observation 　　【中图分类号】R737 【文献标识码】A 【文章编号】1674-7526（2012）12-0045-02 　　膀胱肿瘤是泌尿系统中最常见的肿瘤之一。在我国，男性发病的人数明显多于女性，男性膀胱癌发病率位居全身肿瘤的第八位。其发病原因与多种因素有关。此外其特殊的生理部位，使得在膀胱肿瘤的治疗方面更加难以把握。而一般的膀胱手术只能切除其肉眼所见的肿瘤部位，而并不能除去所有的肿瘤细胞[1]。因此，在膀胱手术后的预防在治疗膀胱肿瘤的方面具有重大的临床意义。我院对56例膀胱肿瘤术后的患者采用了药物膀胱灌注，其临床效果好，现将结果报告如下：