益胃生津汤联合常规西医治疗慢性萎缩性胃炎的临床观察.docVIP

益胃生津汤联合常规西医治疗慢性萎缩性胃炎的临床观察 　　[摘要] 目的 探讨益胃生津汤加减联合常规西医治疗慢性萎缩性胃炎的临床效果。 方法 选择本科2012年4月～2013年12月收治的慢性萎缩性胃炎患者86例，随机分为对照组和研究组各43例，对照组患者给予传统西医治疗，研究组患者在传统西医治疗的基础上给予益胃生津汤加减治疗，治疗4个月后评价两组的治疗效果及相关中医症状评分变化情况。 结果 治疗后研究组患者总有效率为93.0%，明显高于对照组的76.7%，两组比较差异有统计学意义（P0.05）；两组治疗后纳差、嗳气、痞满等中医症状评分均较治疗前降低，且研究组各症状评分明显低于对照组，组间差异有统计学意义（P0.05）。 结论 益胃生津汤辅助西医治疗慢性萎缩性胃炎能有效缓解患者症状，可能对其病理过程有抑制作用，并且不良反应少，安全性高，值得应用。 　　[关键词] 益胃生津汤；慢性萎缩性胃炎；临床效果 　　[中图分类号] R573.3+2 [文献标识码] A [文章编号] 1674-4721（2014）08（b）-0129-03 　　[Abstract] Objective To study the clinical effect of Yiwei Shengjin decoction combined with conventional Western medicine in treatment of chronic atrophic gastritis. Methods 86 cases of patients with chronic atrophic gastritis admitted in our department from April 2012 to December 2013 were randomly divided into control group and study group，each of 43 cases，patients in control group were given with traditional Western medicine；on the basis of traditional Western medicine，patients in the study group were given with Yiwei Shengjin decoction therapy，the decoction was added and subtracted with the disease.After 4 months treatment，therapeutic effect and traditional Chinese medicine symptom score in both groups were evaluated. Results After treatment，the total effective rate of study group was 93.0%，higher than 76.7% of the control group，the difference was significant （P0.05）；the anorexia，belching，fullness score of two groups were all reduced，but the scores of study group were lower than those of control group （P0.05）. Conclusion Yiwei Shengjin decoction assisted Western medicine treatment of chronic atrophic gastritis can effectively relieve symptoms and may can inhibit the pathological process，with fewer adverse reaction and high safety，is worthy of application. 　　[Key words] Yiwei Shengjin decoction；Chronic atrophic gastritis；Clinical effect 　　慢性萎缩性胃炎是一种临床常见病，主要表现为局限性或广泛性胃黏膜固有腺体萎缩，慢性萎缩性胃炎发病缓慢，病程迁延，临床治疗比较困难，伴有肠上皮化生或不典型增生，癌变可能性大[1]。目前临床西医治疗多采用止痛、保护胃黏膜、增强胃动力等方案，效果不甚满意。由于慢性萎缩性胃炎以胃脘部痞满疼痛多见，中医将其归入“胃脘痛