窄谱中波紫外线照射联合口服依巴斯汀治疗玫瑰糠疹的临床观察.docVIP

窄谱中波紫外线照射联合口服依巴斯汀治疗玫瑰糠疹的临床观察 　　[摘要]目的：探讨窄谱中波紫外线照射联合口服依巴斯汀治疗玫瑰糠疹的临床疗效。方法：选取2012年8月～2013年7月笔者科室治疗的92例玫瑰糠疹患者为研究对象，随机分为观察组（46例）和对照组（46例），观察组患者采用窄谱中波紫外线照射联合依巴斯汀治疗；对照组仅口服依巴斯汀治疗，比较两组患者的临床疗效。结果：观察组患者的治疗总有效率达93.48%，对照组为69.57%，两组比较差异具有统计学意义（P0.05）。结论：窄谱中波紫外线照射联合口服依巴斯汀治疗玫瑰糠疹可获得良好的临床疗效，值得临床借鉴和推广。 　　[关键词]紫外线；窄谱；中波；依巴斯汀；玫瑰糠疹 　　[中图分类号]R454.2[文献标识码]A [文章编号]1008-6455（2014）09-0747-03 　　 　　Narrow spectrum UVB rays irradiation combined oral in accordance with the basting clinical observation for the treatment of pityriasis rosea 　　LIN Jing,HUANG Geng-shi,LI Xiao-hong 　　（Department of Dermatology,Guangdong Academy of Medical Science,Guangzhou 510080, guangdong,China） 　　Abstract:Objective To discuss the clinical effect of narrow-band ultraviolet B phototherapy combined with Ebastine in treatment of pityriasis rosea. Methods From 2012 August to 2013 July, 92 cases of patients with pityriasis rosea in our hospital were treated as the research object, randomly divided into observation group (46 cases) and control group (46 cases), the observation group were treated by NB-UVB irradiation combined with Ebastine treatment, the control group only port Do Bea Baskin, to compare the clinical efficacy of two groups of patients.Results The patients in the treatment group the total effective rate was 93.48%,the effective rate of the control was only 69.57% in the treatment group, there were significant differences between the two groups (P0.05). Conclusion Narrow band ultraviolet irradiation combined with Ebastine in treatment of pityriasis rosea can achieve good clinical efficacy,is worthy of reference and promotion. 　　Key words: UVB;narrow spectrum; Ebastine; pityriasis rosea 　　玫瑰糠疹（pityriasis rosea，PR）是一种常见的炎症性皮肤病，好发于躯干和四肢的近侧端，主要表现为椭圆形或圆形淡红或黄褐色斑片，上覆糠秕样鳞屑，自觉瘙痒。本病通常具有自限性，自然病程约4～6周[1]。本文以2012年8月～2013年7月笔者科室收治的92例PR患者为研究对象，采用不同的治疗方法对分组后的患者进行治疗，并观察窄谱中波紫外线（narrow band ultraviolet B，NB-UVB）照射联合口服依巴斯汀治疗PR的临床疗效，现报道如下。 　　 　　1资料和方法 　　1.1一般资料：本文选取笔者科室2012年8月～2013年7月收治的92例PR患者为研究对象，其中有母斑者56例，