纳洛酮对急重症脑梗死的疗效观察.docVIP

纳洛酮对急重症脑梗死的疗效观察 　　【摘要】目的探讨纳洛酮对急重症脑梗死患者的临床疗效。方法回顾性分析2009年1月~2014年1月期间在本院住院治疗的80例急重症脑梗死患者, 其中40例患者给予常规的抗血小板、抗凝等治疗(对照组), 而另40例患者在常规治疗基础上给予纳洛酮治疗(观察组), 对比两组患者的治疗效果。结果对照组基本痊愈8例, 显效13例, 有效6例, 无效13例, 总有效率67.5%；观察组患者基本痊愈13例, 显效15例, 有效7例, 无效5例, 总有效率87.5%, 两组对比差异有统计学意义(P0.05)。结论纳洛酮应用于急重症脑梗死患者的治疗中, 能够和常规治疗起协同作用, 提高治疗效果, 值得临床推广。 　　【关键词】纳洛酮；急重症脑梗死 　　 　　Clinical effect observation on naloxone in the treatment of severe cerebral infarction WANG Hong-min, LI Jun-hong. Chengdu Fifth People’s Hospital, Chengdu 611130, China 　　【Abstract】#8195;Objective#8195;To discuss the clinical effect of naloxone in the treatment of severe cerebral infarction. Methods#8195;80 patients with severe cerebral infarction treated in our hospital during January 2009 to January 2014 were retrospectively analyzed. Among them, 40 cases were treated with routine antiplatelet and anticoagulation treatment (control group), while the other 40 cases were treated with naloxone on basis of routine treatment. Clinical effects of the 2 groups were compared. Results#8195;In control group, there were 8 cases cured, 13 cases with significant effect, 6 cases with effect and 13 cases without effect, and the total effective rate was 67.5%; in observation group, there were 13 cases cured, 15 cases with significant effect, 7 cases with effect and 5 cases without effect, and the total effective rate was 87.5% (P0.05). Conclusion#8195;Naloxone has a synergistic effect with routine treatment in treatment of patients with severe cerebral infarction. It can improve clinical effect and it is worth of clinical promotion. 　　【Key words】#8195;Naloxone; Severe cerebral infarction脑梗死是临床常见的神经内科疾病, 通常是因为颅内供血供氧障碍导致局部的脑组织缺氧造成坏死的一种疾病, 对患者的生活和工作造成了严重的影响。近年来临床急重症脑梗死患者越来越多, 由于病情进展快, 往往会对患者造成一定的致残率［1］, 很多患者治疗后伴随各种后遗症, 临床使用纳洛酮在急重症脑梗死的治疗中辅助常规治疗, 可以一定程度改善致残率和后遗症情况, 提高治疗效果, 帮助患者更好更快的恢复, 现将2009年1月~2014年1月期间研究资料整理总结, 报告如下。 　　1资料与方法 　　1. 1一般资料回顾性分析2009年1月~2014年1月期间在本院住院治疗的80例急重症脑梗死患者, 其中40例患者给予常规的抗血小板、抗凝等治疗(对照组), 而另40例患者在常规治疗基础上给予纳洛酮治疗(观察组)。