准分子激光上皮瓣下角膜磨镶术矫治高度近视.docVIP

准分子激光上皮瓣下角膜磨镶术矫治高度近视 【摘要】nbsp; 目的 评价准分子激光上皮瓣下角膜磨镶术（LASEK）矫治高度近视的疗效。方法 选取高度近视患者27例（54眼），术前近视等效球镜为-6.00 -14.00?D，平均（-8.75±1.27）D。观察术后角膜上皮修复时间、术后视力、角膜上皮下雾状混浊（Haze）、角膜地形图及屈光度数，随访时间为6个月。结果 所有术眼术中及术后均无严重并发症发生。术后角膜上皮修复时间平均为（3.71±0.26）d。术后3?d，裸眼视力≥0.5者48眼（88.9％），≥0.8者19眼（35.2％），术后7?d，裸眼视力≥0.5者54眼（100.0％），≥0.8者47眼（87.0％），术后6个月，裸眼视力均达到或超过术前最佳矫正视力。术后1、3、6个月等效球镜均在-0.50 ＋0.50?D之间，术后1、3、6个月角膜Haze发生率分别为13眼（24.1%）、7眼（13.0%）、2眼（3.7%），但均小于2级，不影响视力恢复。结论 LASEK治疗高度近视视力恢复好且稳定，无明显角膜上皮下雾状混浊及屈光回退。 【关键词】nbsp; 准分子激光上皮瓣下角膜磨镶术 近视 视力 角膜上皮下雾状混浊 nbsp;nbsp;nbsp; Abstract: Objectivenbsp;nbsp; To investigate the effect of laserassisted subepithelial keratectomy（LASEK）for the correction of high myopia. Methodsnbsp;nbsp; LASEK was performed on 54 eyes of 27 myopia patients. The preoperative mean spherical (MSE) was -6.00 -14.00?D, average（-8.75±1.27）D. Postoperative uncorrected visual acuity (UCVA), refractive power, time of epithelial healing and corneal haze were all recorded. Patients were followedup for 6 months. Resultsnbsp;nbsp; No serious complications occurred. The epithelium was healed in a mean （3.71±0.26）d. 3 days after the operations, the UCVA≥0.5 was found in 88.9%(48/54) and ≥0.8 in 35.2% (19/54). 7 days after the operations, the UCVA≥0.5 was found in 100%(54/54) and ≥0.8 in 87.0% (47/54). 6 months after the operations the UCVA was equal with or better than the preoperative best corrected visual acuity (BCVA). 1, 3 and 6 months after the operations, corneal haze was found in 13 eyes（24.1%）, 7 eyes（13.0%） and 2 eyes（3.7%）respectively but it was below grade 2 and had no effect on visual acuity. Conclusionnbsp;nbsp; LASEK is a safe, effective, stable and predictable surgery for myopia. nbsp;nbsp;nbsp; Key words: Laserassisted subepithelial keratomileusis； Myopia； Visual acuity； Corneal haze 　　1999年Camellin［1，2］提出并命名的准分子激光上皮下角膜磨镶术(laserassisted subepithelial keratomileusis, LASEK)，为准分子激光矫治屈光不正开辟了新的研究方向。LASEK治疗低、中度近视的疗效及安全性已得到了认可［13］，我们旨在探讨LASEK治疗高度近视的安全性