ppt课件-agentsusedinthetreatmentofskindisorders.pptVIP

Chapter 43 Agents Used in the Treatment of Skin Disorders The Skin The largest organ Several functions Protective barrier—microbials and trauma Senses temperature changes Secretes wastes through sweat glands Stores fat Synthesizes vitamin D Provides a site for drug absorption Drug Classification of Dermatological Agents Emollients Keratolytics Local anesthetic agents Local antipruritic agents Antibacterial agents Drug Classification of Dermatological Agents Antiviral agents Antifungal agents Anti-inflammatory agents Antiparasiticidal agents Additional Dermatologic Agents Topicals Ointment Gel or jelly Oil Cream Vaginal cream Paste Aerosol foam Aerosol spray Lotion Powder Dermatologic Classifications This presentation will discuss three dermatologic classifications: Topical debriding agents Eczema treatments Psoriasis treatments Several classifications, such as antimicrobials, were discussed in previous chapters and are not discussed here. Topical Debriding Agents Purpose Remove dead skin Promote healing Topical Debriding Agents Made of enzymes General action Digest dead necrotic tissue Specific action Made of enzymes that digest: Collagen: collagenase (Santyl) Fibrin in a blood clot: fibrinolysin (Elase) Eczema Eczema Psoriasis A chronic skin condition Consists of painful reddened papules that form plaques with distinct borders Other patches appear as silvery yellow-white scales Usually located Elbows, scalp, knees, and genitalia Psoriasis Drug agent Alefacept (Amevive) Immunosuppressant Stops the activity of T lymphocytes Given intramuscularly Adverse effects Infection Topical Application Methods Depend on the etiology of the skin problem Require thorough cleansing of the skin before the agent is applied or reapplied Must be applied appropriately or the agents will not work *Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. (continues) (continued) Debriding agents Antineoplastic agents Burn treatment agents Eczema age