专项整治前后Ⅰ类切口手术预防用抗菌药物对比分析.docVIP

专项整治前后Ⅰ类切口手术预防用抗菌药物对比分析 　　[摘要] 目的 调查并分析陕西省宝鸡市中心医院（以下简称“我院”）开展抗菌药物临床应用专项整治活动的成效与不足，为进一步深化抗菌药物专项整治，规范抗菌药物的临床应用提出建议。 方法 随机抽取2010年10~12月（专项整治前）和2013年10~12月（专项整治后）我院Ⅰ类切口手术（甲状腺、乳腺、腹外疝手术）病历各200份，分析整治前后抗菌药物使用率和用药情况。 结果 通过专项整治，我院Ⅰ类切口手术抗菌药物预防使用率由98.5%降为7.0%，药物选择、给药时机、溶媒选择、单次剂量的合理率分别由47.72%、10.66%、52.38%、41.12%升至78.57%、57.14%、100.00%、78.57%，差异均有统计学意义（P 0.05），但仍存在用药疗程合理率无明显提高等问题。 结论 专项整治活动有助于促进抗菌药物的合理使用，建立抗菌药物临床应用管理长效工作机制是必要的。 　　[关键词] 专项整治；Ⅰ类切口手术；抗菌药物 　　[中图分类号] R65[文献标识码] B[文章编号] 1673-7210（2014）06（b）-0134-05 　　 　　Contrastive analysis of perioperative prophylactic application of antibiotics for type Ⅰ incision before and after the special rectification 　　LIU Ziyun LIU Dong ZHANG Xiaoyu ZHANG Jin JIANG Fengli WU Yiping 　　Department of Clinical Pharmacology, Baoji Central Hospital, Shaanxi Province, Baoji 721008 　　[Abstract] Objective To investigate and analysis the effect and inadequacy of the special regulation of the using of antibiotics in Baoji Central Hospital of Shaanxi Province (“our hospital” for short), offer a proposal for constantly deepened to promote the rectification and rational using of antibiotics. Methods 200 cases of type I incision operation (thyroid, breast, abdominal external hernia) from October to December 2010 (before rectification) and 200 cases with the same operation from October to December 2013 (after rectification) in our hospital were randomly selected; rationality of antibiotics usage before and after rectification was contrastive analyzed. Results Through the special rectification, preventive antibacterial rate of type I incision operation reduced from 98.5% to 7.0% in our hospital, reasonable rate of selection of drug, medication timing, selection of solvent, a single dose increased from 47.72%, 10.66%, 52.38%, 41.12% to 78.57%, 57.14%, 100.00%, 78.57%, the differences were statistically significant (P 0.05), but there were still some problems, such as reasonable rate no significant increase in course of prophylactic use. Conclusio