泮托拉唑钠冻干粉剂注射剂对上消化道出血的疗效观察.docVIP

泮托拉唑钠冻干粉剂注射剂对上消化道出血的疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.21.26 　　摘 要 目的：观察泮托拉唑钠冻干粉剂注射剂治疗上消化道出血的临床效果。方法：选取上消化道出血患者100例，按照知情自愿原则，将100例患者随机分为观察组和对照组，每组50例。两组在入院后均给予输血、补液常规治疗，并配合积极有效的临床护理干预措施。观察组在此基础上，应用泮托拉唑钠冻干粉剂注射剂进行治疗，对照组应用奥美拉唑进行治疗。结果：观察组临床治疗总有效率94.0%，显著高于对照组88.0%，组间比较差异具有统计学意义（P0.05）。结论：泮托拉唑治疗上消化道出血能够显著提高患者的临床治疗总有效率，且不良反应较小，具有较高的安全性。 　　关键词 泮托拉唑钠冻干粉剂注射剂 上消化道出血 临床效果 　　Observation of the clinical effect of pantoprazole sodium freeze dried powder injection in the treatment of upper gastrointestinal bleeding 　　Zhi Yanhong 　　Guizhou General Hospital of Shuicheng Mining Group，（Liupanshui City，Guizhou） 553001 　　Abstract Objective：To observe the clinical effect of pantoprazole sodium freeze dried powder injection in the treatment of upper gastrointestinal bleeding.Methods：100 cases with hemorrhage of upper digestive tract were selected accordance with the principle of volunteer.They were randomly divided into the observation group and the control group with 50 cases in each.The two groups were given conventional treatment of blood transfusion，fluid infusion after admission，and combined with effective clinical nursing intervention measures.The observation group were treated with pantoprazole sodium freeze dried powder injection on the basis of conventional treatment.The control group were treated with omeprazole.Results：The total efficiency of clinical treatment of the observation group was 94%.It is significantly higher than that of the control group of 88%.The difference was statistically significante between the two groups（P0.05）.Conclusion：Pantoprazole in the treatment of upper gastrointestinal bleeding can significantly improve the total efficiency of clinical treatment，and less adverse reactions.It also has higher security. 　　Key words Pantoprazole sodium freeze dried powder injection；Hemorrhage of upper digestive tract；Clinical effect 　　上消化道出血是一种常见的较为严重的消化系统疾病，其主要的临床表现为呕血、便血以及不同程度的周围循环衰竭，该疾病具有发病急、病情复杂、病情变化快。患者一旦发生上消化道出血，如果不能给予及时的治疗，会对患者的生命健康造成严重的威胁。因此，对