超声联合钼靶X线在三阴性乳腺癌诊断中的临床价值.docVIP

超声联合钼靶X线在三阴性乳腺癌诊断中的临床价值 　　doi：10.3969/j.issn.1007-614x.2014.20.69 　　摘 要 目的：探讨超声联合钼靶X线在三阴性乳腺癌诊断中的临床价值。方法：2010年1月-2012年12月收治三阴性乳腺癌患者55例，所有患者均经过超声与钼靶X线的诊断。并对两类方法单独诊断结果的符合率与联合诊断结果的符合率进行对比。结果：超声对三阴性乳腺癌患者的单独诊断符合率90.1%，钼靶X线对三阴性乳腺癌患者的单独诊断符合率79.9%，两组数据差异具有统计学意义（P0.05）。两种诊断方法结合后的诊断符合率94.3%。结论：超声联合钼靶X线显著提高了超声与钼靶X线的单独诊断符合率，临床上可将两种方法联用，为患者的后续治疗奠定基础。 　　关键词 超声 钼靶X线 三阴性乳腺癌 临床价值 　　Investigatation of the clinical value of ultrasound combined with mammography in the diagnosis of three negative breast carcinoma 　　Yang Jianguo 　　The Center Hospital of Shandong Energy Xinwen Mining Group Company 271233 　　Abstract Objective：To explore the clinical value of ultrasound combined with mammography in the diagnosis of three negative breast carcinoma.Methods：55 three negative breast cancer patients were selected from January 2010 to December 2012.All of them were diagnosed by ultrasonography and mammography.We compared the results coincidence rate of separate diagnosis of two kinds of methods and combined diagnosis.Results：The consistent rate of separate diagnosis of ultrasound for three negative breast carcinoma was 90.1%.The consistent rate of separate diagnosis of mammography for three negative breast carcinoma was 79.9%.The difference was statistically significant（P0.05）.The consistent rate of combined diagnosis was 94.3%.Conclusion：Ultrasonography combined with mammography can significantly improve the compliance rate of separate diagnosis with ultrasonography or mammography.In clinical，we can use a combination of two methods.It can lay the foundation for follow-up treatment of patients. 　　Key words Ultrasonography；Mammography；Three negative breast carcinoma；Clinical value 　　三阴性乳腺癌（triple negative breast cancer，TNBC）是指雌激素受体（ER）、孕激素受体（PR）与人表皮生长因子受体2（HER2）均为阴性的一类乳腺癌疾病[1]。目前三阴性乳腺癌无较好的治疗方法，并缺乏合理有效的内分泌与靶向治疗，死亡率较高。且此类乳腺癌在医学影像上无明显特征，易与良性病变混淆，因此，高准确率的影像学诊断则是提高患者存活率的关键，我院通过超声与钼靶X线联合对患者进行诊断，取得较好效果，现报告如下。 　　资料与方法 　　2010年1月-2012年12月收治三阴性乳腺癌患者55例，所有患者均符合三阴性乳腺癌的诊断标准与指征。年龄29～58岁，平均（48.9±3.5