Personal Exposure to Polybrominated Diphenyl EthersPBDEs in多溴联苯醚PBDEs在个人暴露.pptxVIP

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Personal Exposure to Polybrominated Diphenyl EthersPBDEs in多溴联苯醚PBDEs在个人暴露.pptx

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Personal Exposure to Polybrominated Diphenyl EthersPBDEs in多溴联苯醚PBDEs在个人暴露

Personal Exposure to Polybrominated Diphenyl Ethers (PBDEs) in Residential Indoor Air Joseph G. Allen, Michael D. McClean, Heather M. Stapleton, Jessica W. Nelson, and Thomas F. Webster Presented by Shaina Stacy December 2010 1 Outline of Presentation Background Structure, commercial uses, exposure pathways and previous studies Study Objectives Methods Area and personal air sampling, laboratory analysis, survey of home characteristics and data analysis Results and Conclusions Strengths Limitations References 2 Background: Polybrominated Diphenyl Ethers (PBDEs) Hydrophobic Persistent in the environment Bioaccumulate in humans and biota Used as fire retardants in consumer products /documents/ehc/ehc/ehc162.htm 3 Background: Commercial Use PBDEs: and http://www.sinoharvest .com; Products: /cnc/polyurethane_foam.htm and /TRADESHOW/DUBAI-ELECTRONICS/VISITOR.HTM 4 Background: PBDE Exposure Pathways and Possible Effects Possible routes of exposure Inhalation, dust ingestion and dermal absorption Possible harmful effects Unknown effects in humans Endocrine disrupting and developmental neurotoxic effects in animal studies 5 Background: Previous Studies Association between penta-like PBDEs in dust collected from residences of first-time mothers and PBDE concentrations in breast milk Limitations of previous studies: Did not measure concentrations of BDE 209 in homes Were not done in the United States Used passive sampling methods, which undersample particulates Collected area samples, which underestimate exposure 6 Study Objectives To quantify indoor air exposure to PBDEs in the home using both personal and ambient air sampling methods To address limitations of previous studies as outlined on the last slide 7 Methods Description of study 20 urban residences in the Greater Boston area in MA, both single- and multi-family Sample based on willingness to participate (nonrandom) January to March 2006 Used both personal and area air sampling methods Air sampling pumps connected t