皮肤解毒汤治疗血虚风燥型慢性湿疹临床研究.docVIP

皮肤解毒汤治疗血虚风燥型慢性湿疹临床研究 　　[摘要] 目的 观察皮肤解毒汤治疗血虚风燥型慢性湿疹的临床疗效。 方法 将2014年3月～2015年12月符合诊断标准和纳入标准的60例患者分为治疗组30例和对照组30例；治疗组中药皮肤解毒汤内服合药膏外用，对照组以氯雷他定合药膏外用。治疗3周，每周为1个疗程。观察两组的疗效和复发情况。 结果 经三个疗程治疗，统计学分析显示，治疗组疗效优于对照组，差异具有统计学意义（P0.05）；两组随访复发情况差异有统计学意义（P0.05）。结论 中药内服能快速缓解慢性湿疹患者的皮损症状，降低慢性湿疹的复发率，临床运用未发现不良反应，值得临床推广运用。 　　[关键词] 皮肤解毒汤；血虚风燥；慢性湿疹；氯雷他定；皮损症状 　　[中图分类号] R275.9 [文献标识码] B [文章编号] 1673-9701（2016）14-0140-03 　　[Abstract] Objective To observe the clinical effect of Pifujiedu decoction in the treatment of blood deficiency and wind dryness type chronic eczema. Methods The 60 patients from March 2014 to December 2015 were divided into two groups according to the diagnostic criteria and inclusion criteria， 30 cases were in the treatment group，the other cases were in the control group. The treatment group accepted Chinese herbal medicine Pifujiedu decoction and ointment， the control group cases were treated with Loratadine and the same ointment of the treatment group. After three weeks， a course of treatment per week， the curative effect and recurrence of the two groups were observed. Results After three courses of treatment， statistical analysis showed the outcome of treatment group was better than the control group， the difference was statistically significant（P0.05）； follow-up of the recurrence， the difference was statistically significant（P0.05）. Conclusion Oral administration of traditional Chinese medicine can quickly relieve symptoms of skin lesions of chronic eczema， reduce the recurrence rate of chronic eczema，clinical application has not found adverse reactions， it is worthy of clinical application. 　　[Key words] Pifujiedu decoction； Blood deficiency and wind dryness； Chronic eczema； Ioratadine； Symptoms of skin lesions 　　皮肤解毒汤系广东省国医大师?P国维教授治疗慢性湿疹的经验方。湿疹是由多种内外因素导致的慢性瘙痒性皮肤病，以皮肤多形性且对称分布、渗出倾向、反复发作、瘙痒和慢性化为主要特征。中医学认为慢性湿疹发病之首因为禀赋，禀赋不耐外邪客于肌肤，迁延反复而致慢性；湿疹发作初期则予解毒利湿为治疗原则；待迁延后期成慢性湿疹，湿邪深陷胶结，则疏利之法甚难奏效，?P师则建议从“湿毒”立论，从脏腑及八纲辨证治疗。我们在临床研究中发现皮肤解毒汤对血虚风燥型慢性湿疹疗效颇佳，现总结如下。 　　1 资料与方法 　　1.1 一般资料