硫酸镁联合硝苯地平治疗妊娠期高血压疗效分析.docVIP

硫酸镁联合硝苯地平治疗妊娠期高血压疗效分析 　　[摘要] 目的 探讨硫酸镁联合硝苯地平治疗妊娠期高血压的临床疗效。 方法 对2014年1月～2015年12月在我院治疗的妊娠期高血压患者92例的临床资料进行回顾性分析。其中研究组47例患者采用联合硫酸镁及硝苯地平治疗，对照组45例患者采用硫酸镁。比较两组的临床疗效。 结果 研究组总有效率显著高于对照组，差异有统计学意义（P0.05）。两组治疗后收缩压与舒张压较治疗前均显著下降，差异有高度统计学意义（P0.01）；治疗后，研究组收缩压与舒张压均显著低于对照组，差异有高度统计学意义（P0.01）。治疗后，24 h尿蛋白量、血细胞比容、血黏度、S/D及RI较治疗前均显著下降，差异有高度统计学意义（P0.01）；治疗后，研究组血黏度、24 h尿蛋白量、血细胞比容、S/D及RI均显著低于对照组，差异有高度统计学意义（P0.01）。 结论 硫酸镁联合硝苯地平治疗妊娠期高血压具有较好的临床疗效，值得临床推广。 　　[关键词] 硫酸镁；硝苯地平；妊娠期高血压；血细胞比容 　　[中图分类号] R720.5 [文献标识码] B [文章编号] 1673-9701（2016）25-0089-03 　　Analysis of magnesium sulfate combined with nifedipine in treatment of pregnancy-induced hypertension syndrome 　　WANG Wenli 　　Department of Gynecology and Obstetrics， Donggang Hospital of Traditional Chinese Medicine in Liaoning Province，Donggang 118300，China 　　[Abstract] Objective To discuss clinical efficacy of magnesium sulfate combined with nifedipine in the treatment of pregnancy-induced hypertension syndrome. Methods Clinical data of 92 cases with pregnancy-induced hypertension syndrome from Jan 2014 to Dec 2015 were respectively analyzed. 47 cases of study group were treated with magnesium sulfate combined with nifedipine， and 45 cases of control group were treated with magnesium sulfate. Clinical efficacy of two groups was compared. Results Total effective rate of study group was higher than control group（P0.05）. After treatment， SBP and DBP of two groups were lower than those before treatment（P0.01）； After treatment，SBP and DBP of study group were lower than control group（P0.01）. After treatment，the blood viscosity，24 h urinary protein， hematocrit， S/D and RI of two groups were lower than those before treatment（P0.01）； After treatment， the blood viscosity， 24 h urinary protein， hematocrit， S/D and RI of study group were lower than control group（P0.01）. Conclusion Magnesium sulfate combined with nifedipine in the treatment of pregnancy-induced hypertension syndrome shows good clinical efficacy， worthy of clinical promotion. 　　[Key words