蛋白质相互作用网络演化模型研究进展.pdfVIP

JournalofComputerApplications ISSN 1001??9081 2013??03??0l ?????????2013??33(3)??816??820??829 CODEN JYIIDU http??????www??joca??cn ???±???1001??9081(2013)03??0816??05 doi??10??3724??SP??J??1087??20l3??00816 ???????????????????????о???? ?????????? ????? ???????? (???????????????????????410082) ($?????????????? luojiawei@hnu??edu??cn) ? ????о????????????????????????????????????????????????????γ?????????????? ?塣?? ?????????????????????????????????? ???????????????????????Щ??????????????? ?? ????????????????????г?????Щ???????? ??????????????????????????????? ???????????????? ?????????о???????????????????????????????????????????????????????????? ???????????? ????????????????????? ???????????????????????? ?????????????????????? ???????? ??????????????????ο??? ?????????????????????磻??????????????? ?????????TP399 ????????A Surveyonevolutionarymodelsofprotein-proteininteractionnetwork LUOJiawei??LIANGCheng??SONGDan??LIGuanghui (School InformationScienceandEngineering??HunanUniversity??ChangshaHunan410082??China) Abstract??TheresearchontheevolutionarymechanismsandmodelsofProtein??ProteinInteraction(PPI)networkis significantforunderstandingtheevolutionofthebiologicalsystemsaswellastheformationprocessoftheorganisms??Sofar?? therehavebeenkindsofmodelsbasedondifferentevolutionarymechanisms??Allofthesemodelsexhibitcertaintopological characteristicsemergingfrom theprotein??proteininteractionnetworks??whilesomelimitationsexistsimultaneously??Thispaper focusedonseveralclassicprotein??proteininteractionnetworkmodels??analyzingthemainideasofthesemodelsandcomparing thetopologicalcharacteristicsderivedfrom them with thoseofrealprotein