结构生物学sturcture biology explore-28.pdfVIP

217 Clamp loaders and sliding clamps David Jeruzalmi*??, Mike O’Donnell? and John Kuriyan*?§ A coherent view of the structure and function of DNA transcription in T4 bacteriophage [22], DNA repair and polymerase processivity factors (sliding clamps and clamp cell cycle control [23]. loaders) is emerging from recent structural studies. Crystal structures of sliding clamps from the T4 and RB69 Sliding clamps are loaded onto DNA by specialized protein bacteriophage