广东省高等医学院校教学医院评审指标体系.ppt

Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: A meta-analysis Lecturer：Caiqingxian Email：cqx200000@ What’s meta-analysis Combination of combinable individual articles A study method of EBM Evidence-based medicine Current best evidence Clinician’s experience Patient’s demand Evidence ranked by ASCO What’s the best evidence? How to do a meta-analysis Clinical question Evidence collection Appraise Integrate Evaluate Title Why should we conduct this meta-analysis? HBV cause too much death The disadvantage of INF and NA Some RCTs compare INFαand Tα-1 How to do a meta-analysis Clinical question Evidence collection Appraise Integrate Evaluate 2. Method Level 1 Meta-analysis or systemic review Level 3 non randomized cohort studies Level 2 single large sample randomized control trials Level 4 cross selection survey without control Level 5 expert opinion, case report, descriptive study Problem Intervention