不同辅料膏方的制备工艺研究.PDF

·820· 中草药 Chinese Traditional and Herbal Drugs 第 44 卷 第 7 期 2013 年 4 月 不同辅料膏方的制备工艺研究 刘 霞，胡兰贵，冯玛莉，席啸虎，张小慧，仝立国 山西省中医药研究院，山西 太原 030012 摘 要：目的 优选不同辅料膏方制备工艺的最佳条件参数。方法 以膏方的性状特征、成膏率及药材检出情况为控制指标， 采用多指标综合评分法评价膏方成型性；以辅料的使用量（A）、清膏（B）和成品膏（C）的相对密度为 3 个因素，采用星 点设计进行试验，优选膏方制备工艺。结果 4种不同辅料膏方的制备工艺分别为红糖：A1 18%～23%、B1 1.210～1.260、 C1 1.310～1.360；鹿角胶：A2 14%～16%、B2 1.200～1.250、C2 1.230～1.270；龟甲胶：A3 12%～15%、B3 1.190～1.230、 C3 1.210～1.240；阿胶：A4 5.0%～8.0%、B4 1.190～1.220、C4 1.190～1.220。结论 优选的不同辅料的膏方制备工艺参数均 准确可行，质量符合要求。 关键词：膏方；辅料；制备工艺；相对密度；质量控制 中图分类号：R283.6 文献标志码：A 文章编号：0253 - 2670(2013)07 - 0820 - 05 DOI: 10.7501/j.issn.0253-2670.2013.07.009 Preparation technology of paste with different adjuvants LIU Xia, HU Lan-gui, FENG Ma-li, XI Xiao-hu, ZHANG Xiao-hui, TONG Li-guo Shanxi Institute of Traditional Chinese Medicine, Taiyuan 030012, China Abstract: Objective To explore the best parameter in the preparation technology of paste with different adjuvants. Methods The appearance, the paste rate, and herb detection were selected as composite indicators. The multi-index comprehensive score method was used to evaluate the paste formability. Central composite design was used to optimize the preparation technology of paste by taking the adjuvant amount (A), the relative density of extract (B) and refined paste (C) as factors. Results The best condition in the paste preparation process with different adjuvants was as follows: brown sugar (A1 18%—23%, B1 1.210—1.260, and C1 1.310—1.360), Cervi Cornus Colla (CCC, A2 14%—16%, B2 1.200—1.250, and C2 1.230—1.270), Testudinis Carapacis et Plastri Colla (TCPC, A3 12%—15%, B3 1.190—1.230, and C3 1.210—1.240), Asini Corii Colla (ACC, A4 5.0%—8.0%, B4 1.190—1.220, and C4 1.190—1.220). Conclusion The parameters in the preparation technology of the paste with different adjuvants are accurate and feasi