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A model of cancer chemotherapy on several Solution
PAGE \* MERGEFORMAT 8
A model of cancer chemotherapy on several Solution
[Abstract] were using Bernoulli equation, Riccati equation method and Mathematica, to discuss a general solution model for cancer chemotherapy.
[Keywords:] model of cancer chemotherapy; separation of variables; Bernoulli equation; Riccati equation; Mathematica software
In [1] Chapter 5, Section 6, of the natural growth model, to establish a simple model of cancer chemotherapy:
x’x = (r-kx)-smx (1)
Dose of study drug effects on tumor growth, in which x is a function of time t, that tumor size, m, r, k, s are constant, m is the dose, r is the constant activity of tumor cells, k and environment for the growth of tumor cells in patients with immune system that is relevant, s is the effectiveness of drug-related.
[1], separation of variables method to solve equation (1), by equation (1) the general solution: When the drug dose mr24ks time, x (t) = l + ωtan (ω (c-kt)). Where λ1 = r- r2-4ksm2k, λ2 = r + r2-4ksm2k, λ = r2k, l = r2k, ω = smk-(r2k) 2
If no special statement, the study λ1, λ2, λ3, l, ω are specific to the above values. C, C1, C2, said integration constant.
General solution of the equation, [1] conclude that: If a small dose of chemotherapy to eliminate mr24ks lesions. Therefore, this model in pharmacology, treatment of pathological studies and simulation experiments are extremely valuable.
This research uses Bernoulli equation, Riccati equation method and Mathematica, to discuss the general solution of the model cancer chemotherapy, given equations (1) separation of variables in addition to several other than the new method is provided for teachers in the teaching process reference so that students develop thinking, comprehensive application of knowledge has been learned, and learn new knowledge to solve differential equations.
2 equation (1) A new solution of several
[2] introduced the method for solving the Bernoulli equation. Riccati Equation meth
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