About TACE with thalidomide and traditional Chinese medicine clinical observation of treatment of advanced liver.docVIP

 PAGE \* MERGEFORMAT 10 About TACE with thalidomide and traditional Chinese medicine clinical observation of treatment of advanced liver Of: Zhao Zenghu Liujun Tang, Zhang Weilian, Cheng-Yun Li, Liu Xiufang, Ding Ruiliang [Keywords:] thalidomide, in advanced liver cancer, hepatic artery embolization, vascular endothelial growth factor, Chinese medicine Chemoembolization (TACE) is widely recognized as an effective treatment of advanced liver cancer one way to make tumor cells necrosis, tumor shrinkage, symptomatic relief [1], in some cases significantly reduced due to tumor re-access to surgery opportunities. However, peripheral embolism in tumor angiogenesis and often new collateral circulation is an important factor in causing tumor recurrence [2]. vascular endothelial growth factor (VEGF) is the most important tumor angiogenic factors, not only proliferation and tumor angiogenesis, but also directly involved in the invasion and metastasis [3]. Thalidomide (thalidomide) could significantly inhibit tumor angiogenesis and VEGF secretion, increased apoptosis, tumor growth inhibition [4] . TACE with the author and the spleen qi thalidomide treatment of advanced liver cancer medicine do clinical research, are reported below. 1 Materials and Methods 1.1 ① inclusion criteria were all patients with primary hepatocellular carcinoma confirmed by pathology, ② no serious liver and kidney damage, ③ Karnofsky score of 70 or above, ④ expected survival of 3 months or more, ⑤ without portal vein cancer suppository, ⑥ without esophageal varices based on general information .1.2 lt;”China diagnosis and treatment of common malignant tumors specificationgt;gt; [5] for diagnosis and clinical staging. to cases of single-blind method selected randomly divided into 2 groups, treatment group 45 patients, 35 males and 10 females, aged 39 to 68 years, mean 52.5 years, of which 9 cases of stage Ⅱ, Ⅲ of 36 cases. the control group, 42 cases, 31 males and 11 females, aged 41