Acute respiratory distress syndrome pathogenesis diagnosis and treatment progress.docVIP

 PAGE \* MERGEFORMAT 23 Acute respiratory distress syndrome pathogenesis diagnosis and treatment progress Keywords:: Acute respiratory distress syndrome (aRDS), acute lung injury (aLI) pathogenesis diagnosis and treatment of Acute respiratory distress syndrome (acute respiratory distress syndrome, aRDS), previously known as adult-onset multi-(adult) respiratory distress syndrome, is caused by a variety of reasons acute respiratory failure in clinical practice in order to respiratory distress, refractory hypoxemia and non-cardiogenic pulmonary edema is characterized by. aRDS is not an independent disease. As a continuous pathological process in its early stage of acute lung injury (acute lung injury, aLI), moderately or severely aLI that aRDS 〔 1〕 . aRDS or in combination with advanced multi-induced multiple organ dysfunction syndrome (multiple organ dysfunction syndrome, mODS), and even multiple organ failure (multiple organ failure, mOF), dangerous condition, the prognosis is poor, case fatality rate as high as 50% to 60% . Is now on its pathogenesis, diagnosis, and treatment of a number of advances to do a brief introduction. 1 Pathogenesis aRDS the pathogenesis is still unclear. Some factors have directly damage alveolar - capillary membrane (aCM), leading to aLI, such as high concentrations of harmful gases such as oxygen inhalation, the first injury of alveolar epithelial cells. When aspiration, pH ≤ 2 in the stomach contents of the aCM severe chemical injury; the same time, food remnants and gastric juice itself can also be congestion and pollution, respiratory tract, affecting ventilatory function. Diffuse pneumonia-induced acute respiratory failure, whether it should be classified as aRDS, there are still controversial. Are inclined to physiological indicators and other relevant as long as the blood-gas up to standard, should be considered as aRDS. The aRDS in the pathogenesis of more is the primary disease and the incentive away from the lungs, h